Tendoncel is a gel which can be applied directly onto the skin of the elbow. Tendoncel gel contains a mixture of growth factors (a small substance which encourages cells to grow) which help the tendon to repair and heal. A clinical trial of tendoncel in people with severe tennis elbow showed improvements in elbow pain.If tendoncel was licensed in the UK, it would provide a less invasive treatment option to people with severe or prolonged tennis elbow which may delay the need for surgery and improve symptoms.
Vosoritide is in clinical development for the treatment of achondroplasia. Achondroplasia represents the most common form of short-limb dwarfism, a condition where the bones in the arms and legs do not form properly and are shorter than normal. Patients with achondroplasia have a short stature, an enlarged head with a prominent forehead, bowed legs, ear problems, respiratory issues, compression of the spinal cord, as well as short fingers, toes, lower legs and upper arms. No pharmacologic therapies have been approved for achondroplasia in the EU.