Veliparib is a new oral drug that is being developed for patients with HER2- breast cancer that is advanced and cannot be removed completely through surgery. The drug acts by targeting specific enzymes involved in the repair of damaged DNA that helps the body to kill cancer cells while allowing ordinary cells to survive. Veliparib is being developed to be used in combination with the chemotherapy drugs paclitaxel and carboplatin. If licenced, this combination will offer an additional treatment option for patients with HER2- metastatic or locally advanced unresectable BRCA-associated breast cancer.
Seviprotimut-L is a type of cancer vaccine that is being developed for the treatment of adult patients with malignant melanoma who have had surgical resection. It is designed to stimulate the body’s immune system to fight cancer cells, to stop the cancer coming back. Seviprotimut-L is injected under the skin in different parts of the body. The unique way it acts may offer a new treatment option for malignant melanoma patients after surgery.