Selinexor is in clinical development for the treatment of adults with advanced unresectable dedifferentiated liposarcoma (DDLS). Liposarcoma is a malignancy of fat cells and represents the most common form of soft tissue sarcoma. The prognosis varies depending on tumour site, size, grade, and histologic subtype. DDLS occurs when a low-grade tumour changes and newer cells […]
Selinexor, in addition to bortezomib and low-dose dexamethasone, is in clinical development for the treatment of adults with relapsed or refractory multiple myeloma (RRMM) who have received 1 to 3 prior therapies. MM is a rare, incurable cancer of the plasma cells in the bone marrow where large amounts of abnormal plasma cells are produced […]
Selinexor in combination with low-dose dexamethasone are in development for the treatment of patients with penta-refractory multiple myeloma who have received at least five prior therapies. MM is a rare, incurable cancer of the plasma cells in the bone marrow where large amounts of abnormal plasma cells are produced and interfere with the production of […]
Selinexor is in clinical development for the endometrial cancer maintenance therapy after combination chemotherapy. Endometrial cancer (uterine cancer) is a common cancer that affects the female reproductive system and starts when cells in the endometrium (the inner lining of the uterus) start to grow out of control. It is more common in women who have […]
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