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Drugs

December 2017

Lenadogene Nolparvovec (GS-010) for Vision Loss from Leber’s Hereditary Optic Neuropathy Due to Mutation of the ND4 Gene

There are currently very few treatment options for LHON. Most treatment methods are used to support the patient rather than cure them. Lenadogene nolparvovec is a new gene-targeted treatment intended for vision loss caused by LHON due to an alteration in a specific gene. As a genetic medicine, lenadogene nolparvovec could be a promising option …

Drugs

September 2017

Netarsudil plus latanoprost (Roclatan) for glaucoma or ocular hypertension

Glaucoma describes a group of disorders characterised by sight loss. Glaucoma is generally associated with high pressure in the liquids inside the eye but it can happen when the pressure level is normal. Individuals with consistently high eye pressure are at risk of developing glaucoma. Glaucoma does not normally cause any symptoms but once eye …

Drugs

April 2017

Brolucizumab (ESBA1008; RTH258) for neovascular age-related macular degeneration (nAMD)

Age-related macular degeneration (AMD) is a major cause of visual impairment in older adults in the UK. It has three stages – early, intermediate, and late – and can occur in one or both eyes. It is possible for one eye to be at the early stage and the other at late stage. There are …

Drugs

November 2016

Dexamethasone intracanalicular insert (Dextenza) for pain and inflammation following cataract surgery

Dexamethasone intracanalicular insert is a new drug that is placed into the canaliculus of the eye to treat pain and inflammation in people who have had cataract surgery. A cataract is when the lens in the eye becomes cloudy causing blurred vision. Cataracts are very common and usually affect older adults. More than 300,000 cataract …

Drugs

September 2016

XG 102 for post-operative inflammation and pain following cataract surgery

XG 102 is a new drug injected into the eye to treat pain and inflammation in people who have had a cataract operation. A cataract occurs when the lens in the eye becomes cloudy causing blurred vision. Cataracts are very common and usually affect those over the age of 65 years. More than 300,000 cataract …

Reviews

September 2016

SUMMARY – New and emerging health technologies for corneal disorders

The NIHR Horizon Scanning Research and Intelligence Centre (HSRIC) has completed a horizon scanning review that identifies new and emerging technologies and procedures for the treatment of corneal disorders. This work was undertaken in response to a question raised by the James Lind Alliance Priority Setting Partnership on Sight Loss and Vision. Corneal disorders may …

Reviews

September 2016

REVIEW – New and emerging health technologies for corneal disorders

The NIHR Horizon Scanning Research and Intelligence Centre (HSRIC) has completed a horizon scanning review that identifies new and emerging technologies and procedures for the treatment of corneal disorders. This work was undertaken in response to a question raised by the James Lind Alliance Priority Setting Partnership on Sight Loss and Vision.   Corneal disorders …

Drugs

September 2016

Lifitegrast for dry eye disease

Lifitegrast is a new drug to treat the signs and symptoms of dry eye disease. Dry eye disease occurs when the eyes do not make tears properly, the tears are not of the correct consistency, or tears evaporate too quickly. This leads to inflammation in the front surface of the eye, and discomfort or problems …

Devices

July 2016

Navilas® 577 laser system for retinal laser photocoagulation

The Navilas® 577 laser system is a device developed by OD-OS GmbH and distributed by Instinctive Limited for treating patients who require retinal laser photocoagulation. The technology is intended for use in the treatment of clinically significant diabetic macular oedema, proliferative diabetic retinopathy, sub-retinal neovascularisation, central and branch retinal vein occlusion, lattice degeneration and retinal …

Drugs

June 2016

Medidur for non-infectious posterior uveitis – second line

Uveitis is an inflammation that affects the lining of the eye. It can lead to eye pain, eye redness, headaches, and problems with vision that can become permanent. It may be caused by an infection, but in many cases the cause of uveitis is unknown. Medidur is a new drug implant that is injected straight …

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