Roxadustat for Renal Anaemia in Chronic Kidney Disease
Roxadustat is a product in development that can be taken orally as a tablet. It has the potential to stimulate the growth of red blood cells by increasing the body’s own production of EPO in patients with CKD who may be on dialysis or pre‐dialysis. If approved for the treatment of anaemia in this population, roxadustat will provide an alternative treatment option that offers a likely reduction in the need for supplemental iron as an advantage.
Fexapotide Triflutate for Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a medical term that is used to describe enlargement of the prostate gland. It is not a cancer and is usually not a serious threat to health if well-treated. Most males aged 50 years and above develop BPH.
Nefecon (targeted-release budesonide formulation) for IgA Nephropathy (Berger’s disease)
Budesonide is a steroid drug which reduces inflammation. Nefecon is a new oral formulation of budesonide that is designed to specifically deliver the drug to a place in the intestine where most of the immune cells producing IgA are located. This has the potential advantage of targeting the underlying process that causes IgAN with significantly fewer side effects when compared to the generally used systemic steroids such as prednisone, (which is delivered throughout the whole body). If licenced, Nefecon has the potential to become the first disease-specific treatment for IgAN.
PERiPLEX for the detection of acute infection in peritoneal dialysis
PERiPLEX® is a point-of-care test for the detection of markers of infection (peritonitis) in people undergoing peritoneal dialysis for end stage renal disease. It is designed to be suitable for self-testing. The assay has been developed by Mologic Ltd. and may enable people to test for the presence of acute infection in their own home.
Plazomicin for complicated urinary tract infection
Serious infections caused by Gram-negative bacteria are becoming increasingly resistant to commonly prescribed antibiotics and are a serious global concern. If licensed, plazomicin will offer a treatment option for those patients who have a complicated urinary tract infection or acute pyelonephritis caused by multi-drug resistant Gram-negative bacteria, a group who currently have few effective and …
InFlow intraurethral valve-pump for atonic bladder
The inFlow™ Intraurethral Valve-Pump (the inFlow™ device) developed by Vesiflo is a nonsurgical urinary device for women with atonic bladder due to impaired detrusor contractility (IDC). The inflow device allows women with IDC to urinate without the need to catheterise daily or to use an indwelling catheter and urine drainage bag.
Low dose desmopressin lyophilisate (Noqdirna) for nocturia in adults
Producing too much urine at night is the main cause of nocturia (the need to wake up at night to urinate). Although it affects a large number of men and women, particularly as they get older, nocturia is often not recognised as a separate condition and treated with medications for overactive bladder or enlarged prostate …