Secukinumab is in clinical development for adult patients with moderate to severe hidradenitis suppurativa (HS). HS is a painful, long term skin condition that causes abscesses and scarring on the skin. The exact cause of HS is unknown, but it occurs near hair follicles where there are sweat glands, usually around the groin, bottom, breasts […]
Cabozantinib is being developed for the treatment of progressive differentiated thyroid cancer (DTC). Thyroid cancer is rare, and DTC is the most common type of this. It is usually found by a hard lump on the neck that does not move and may grow. It can cause a sore throat, neck pain, hoarseness, and difficulty […]
Baloxavir marboxil is in clinical development for the treatment of paediatric patients 1 to <12 years of age with influenza. Influenza or ‘flu’ is a common virus infection which causes high temperature, body aches, tiredness, cough, sore throat, headache, diarrhoea and nausea. Flu is usually spread by coughs and sneezes and occurs in annual flu […]
Merkel cell carcinoma (MCC) is a rare type of skin cancer that starts in neuroendocrine cells. Those frequently exposed to ultraviolet light and those with weakened immune systems are most at risk of developing MCC. Symptoms include lumps on the skin, usually found where the skin is most exposed to direct sun. MCC is an […]
Atezolizumab is in clinical development for the adjuvant treatment of high-risk locally advanced squamous cell carcinoma of the head and neck (SCCHN), for patients who have received definitive local therapy. SSCHN is the most common type of head and neck cancer and it develops from the mucosal epithelium in the oral cavity, pharynx and larynx. […]
Quizartinib is in development for the treatment of newly diagnosed, fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) positive acute myeloid leukaemia (AML), an aggressive, type of cancer that starts in the blood-forming cells of the bone marrow, and often quickly moves into the blood as well. AML typically develops rapidly and is fatal unless […]
Venetoclax with dexamethasone is currently in clinical development for the treatment of patients with multiple myeloma (MM). MM, also known as myeloma, is a type of bone marrow cancer. Bone marrow is the spongy tissue at the centre of some bones that produces the body's blood cells. It is called MM as the cancer often […]
Triheptanoin is being developed for the treatment of long-chain fatty acid oxidation disorders (LC-FAOD). LC-FAOD is a group of six rare and ultra-rare life-threatening genetic disorders in which the body is unable to convert dietary fatty acids into energy. This inability to produce energy from fat can lead to severe depletion of glucose in the […]
Nivolumab is in clinical development for the adjuvant and neoadjuvant treatment of adults with localised renal cell carcinoma (RCC) who are undergoing surgical removal of a kidney. RCC is a common form of kidney cancer caused by the growth of a tumour in the cells lining the inside of small vessels in the kidney, known […]
Pegcetacoplan is in clinical development for the treatment of geographic atrophy of the macula, secondary to age-related macular degeneration (AMD). AMD is an eye disease that most commonly occurs in people aged over 70 years that affects the middle part of the vision. Some patients with AMD will develop geographic atrophy, which is an advanced […]
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