Dasiglucagon is in clinical development for treating hypoglycaemia due to congenital hyperinsulinism (CHI) in children. CHI is an inherited disorder in which the body releases insulin even when it is not needed. Insulin is a hormone that helps control blood glucose (sugar) levels by driving glucose into the cells of the body. In hyperinsulinism, the […]
Dupilumab is in clinical development for the treatment of chronic spontaneous urticaria for people who still have symptoms despite previous treatment. Urticaria is a skin disorder where red, raised, itchy rashes appear on the skin. Urticaria is considered chronic once symptoms have been present for six weeks or longer and appear almost daily. Spontaneous urticaria […]
Pembrolizumab in combination with gemcitabine plus cisplatin is being developed for patients with advanced/unresectable biliary tract cancer (BTC). BTC is a rare type of cancer that affects bile ducts and the gallbladder. Bile ducts are tubes that connect the gallbladder and liver to the small bowel. Bile is produced in the liver and stored in […]
Nivolumab in addition to docetaxel is in clinical development for the treatment of adult males with advanced, castration-resistant prostate cancer. Prostate cancer is a common cancer caused by the growth of a tumour on the prostate gland. Advanced prostate cancer is a form of prostate cancer where the tumours have spread to other areas of […]
Dupilumab is in clinical development for the treatment of prurigo nodularis (PN) for people who have not responded to or cannot have corticosteroid treatment. PN is a chronic skin disorder in which people have firm, raised bumps on the skin known as nodules. The nodules are very itchy and itching the affected area can worsen […]
Pembrolizumab in combination with pemetrexed and cisplatin is in clinical development for thetreatment of adult patients with advanced malignant pleural mesothelioma (MPM). MPM is a rarevariation of cancer that affects the internal chest wall and the outer linings of the lungs.Mesothelioma is often diagnosed at an advanced stage and surgery is not always possible.Treatment is […]
Durvalumab is in clinical development for previously untreated patients with hepatocellular carcinoma (HCC), the most common type of liver cancer that develops in liver cells known as hepatocytes. Typically, this type of cancer occurs in patients with underlying chronic liver disease and scarring of the liver caused by long-term liver damage (cirrhosis), as a result […]
Epcoritamab is currently in development for treatment of diffuse large B-cell lymphoma (DLBCL).DLBCL is a cancer of B cells (a type of immune cell) and the most common type of fast-growingnon-Hodgkin’s lymphoma (NHL). In DLBCL, the body makes abnormal B cells which build up inlymph nodes or other body organs. The affected lymphocytes start to […]
The combination of sintilimab and pemetrexed and platinum chemotherapy is in clinical development for the treatment of advanced or metastatic non-squamous non-small cell lung cancer (NSCLC). NSCLC makes up the majority of lung cancers in the UK. Advanced cancers can be locally advanced or metastatic. Locally advanced NSCLC is when the cancer has grown into […]
Nivolumab is in clinical development for the adjuvant treatment of stage IB-IIIA non-small cell lung cancer (NSCLC). NSCLC occurs due to tumours forming in the lung and is the most common form of lung cancer. Stage IB-IIIA disease comprises of a range of tumours from 3cm to larger than 7cm in size and have little […]
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