Benralizumab in addition to mometasone furoate is in development for the treatment of severe nasal polyposis/polyps. Nasal polyps are painless soft growths inside the nose. The exact cause is still unknown but asthma and a bad reaction to aspirin are known to increase the risk of developing the disease. Nasal polyps contain inflammatory fluid and […]
Benign prostatic hyperplasia (BPH) is a medical term that is used to describe enlargement of the prostate gland. It is not a cancer and is usually not a serious threat to health if well-treated. Most males aged 50 years and above will develop BPH. As the prostate gets bigger, it can place pressure on the […]
Benign prostatic hyperplasia (BPH) is a medical term that is used to describe enlargement of the prostate gland. It is not a cancer and is usually not a serious threat to health if well-treated. Most males aged 50 years and above develop BPH. As the prostate gets bigger, it can place pressure on the bladder […]
Bempedoic acid as a monotherapy, or in combination with ezetimibe, is in clinical development for high risk and very high risk people with primary hypercholesterolaemia or mixed dyslipidaemia. Abnormal levels of lipids in the blood characterises dyslipidaemia. High levels of cholesterol in the blood (hypercholesterolemia) may be caused by inherited genetic defects as seen in […]
Belzutifan is in clinical development for the treatment of von Hippel-Lindau (VHL) disease-associated clear cell renal cell carcinoma (ccRCC). VHL is a hereditary disease that results in the body producing an increased amount of the protein hypoxia inducible factor (HIF) - 2alpha. This leads to an increased risk of tumours developing in various parts of […]
Belumosudil is in clinical development for the treatment of chronic graft-versus-host disease (cGVHD). cGVHD is an immune-mediated, inflammatory disease with potential fibrotic manifestations in which immune cells from the graft attack the recipient cells after a haemopoietic stem cell transplantation (HSCT). cGVHD is characterised by inflammation and fibrotic processes which can lead to chronic disability […]
Belimumab is in clinical development for the treatment of adults with active lupus nephritis (LN) who are uncontrolled on current standard of care. LN is a complication affecting kidney function brought on by systemic lupus erythematosus (SLE), a chronic autoimmune, inflammatory disease that affects different organs. Around a third of people suffering with SLE will […]
Belimumab in combination with a cycle of rituximab is in clinical development for adults with Systemic Lupus Erythematosus (SLE). SLE is an autoimmune disease where the body’s immune system attacks its own tissues and organs. Patients will often have periods where their symptoms flare-up and periods where their symptoms settle down. Mild SLE can cause […]
Belantamab mafodotin is in clinical development for the treatment of multiple myeloma (MM) in patients who are refractory or have relapsed to prior treatments. MM is a rare, incurable cancer of the plasma cells in the bone marrow where large amounts of abnormal plasma cells are produced and interfere with the production of red and […]
BCX7353 is in clinical development for routine prevention of angioedema attacks in patients with hereditary angioedema (HAE). HAE is a rare genetic disorder of blood vessels characterised by recurrent episodes of severe swelling (angioedema) below the skin which often affect the face, throat, stomach, genitals, hands or feet, causing discomfort and pain. HAE may be […]
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