This search function provides links to outputs produced by NIHR Innovation Observatory. These are briefing notes or reports on new or repurposed technologies. This search will not return all technologies currently in development as these outputs are produced as required for our stakeholders.

Innovation Observatory > Reports > Other



September 2021

Ritlecitinib for alopecia areata

Ritlecitinib is in clinical development for the treatment of patients with alopecia areata (AA). AA is a disease that develops when the body attacks its own hair follicles (where the hair grows from), which can cause hair loss as small round patches of baldness anywhere on the body. Most commonly, this occurs on the scalp …


June 2018

Granexin Gel for Diabetic Foot Ulcers

When blood sugar levels are high or fluctuate regularly, as in people with diabetes, skin that would normally heal may not properly repair itself because of nerve damage. As a result, even a mild injury can start a foot ulcer. Granexin gel contains the peptide ACT1, which possesses potential anti-inflammatory and regenerative properties when administered topically to diabetic foot ulcers. If licensed, granexin gel may offer an additional therapy option for diabetic foot ulcers which are a particularly difficult-to-treat chronic wound type.


September 2016

Visualase™ system for minimally invasive soft tissue ablation

The Visualase™ system, developed by Medtronic plc, is indicated to necrotize or coagulate soft tissue through interstitial thermal therapy under MRI guidance. The Visualase™ system comprises a cooled laser applicator and a working station containing a peristaltic pump for circulating coolant (saline) through the applicator, a diode laser energy source and a computer with MRI analysis software …


August 2016

Mepolizumab (Nucala) for relapsed or refractory eosinophilic granulomatosis with polyangiitis – second line add on therapy

Eosinophilic granulomatosis with polyangiitis is a rare disease that causes inflammation of small and medium sized blood vessels. The lungs and skin are commonly affected, but it can affect other organs including the heart, kidneys, nerves and bowels. Symptoms can include high temperature, tiredness, muscle and joint pain, shortness of breath, rapid weight loss, and …


December 2015

ivWatch Model 400 patient monitor for continuous monitoring of IV sites

The ivWatch Model 400 patient monitor helps doctors and nurses find out whether a drip in the vein is leaking into the surrounding tissue. If this happens, it can cause pain, infection, tissue damage and loss of limb. The ivWatch system contains a patient monitor, a light, and a single-use container that secures the light …


September 2014

SensiumVitals® vital signs monitoring patch

SensiumVitals® is a wireless, wearable, disposable patch, which monitors vital signs of patients to provide early identification of physical deterioration and opportunities for early intervention.


October 2013

OrganOx® metra™ for liver preservation during transplantation

The OrganOx® metra™ is a portable device in development by OrganOx Limited that is intended to be used during liver transplantation to preserve and maintain the donated liver for up to 24 hours between the point of retrieval and transplantation.


August 2006

Optiscope for internal examinations and surgical operations

Optiscope is a disposable rigid endoscope that is in development for internal examinations and surgical procedures. The first product is a 10mm diameter laparoscope. Future products are planned to be as small as 2.5mm.

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