Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab in addition to trastuzumab and chemotherapy for HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma – First-line	Pembrolizumab (Keytruda; MK-3475) , Trastuzumab (Herceptin; RG-597)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Pembrolizumab in combination with Axitinib for Metastatic Renal Cell Carcinoma – first line	Axitinib (Inlyta; AG-013736) , Pembrolizumab (Keytruda; MK-3475)	Renal cell carcinoma (RCC)	Renal Cancer	2018	View \| Download
Pembrolizumab in Combination with Epacadostat for Unresectable or Metastatic Melanoma	Epacadostat (INCB024360) , Pembrolizumab (Keytruda; MK-3475)	Melanoma	Skin Cancer	2018	View \| Download
Pembrolizumab in combination with gemcitabine and cisplatin for previously untreated advanced/unresectable biliary tract cancer	Cisplatin (Platinol) , Gemcitabine (Gemzar; gemcitabine hydrochloride) , Pembrolizumab (Keytruda; MK-3475)	Biliary tract cancer	Gastrointestinal Cancer	2021	View \| Download
Pembrolizumab in combination with ipilimumab for advanced non-small cell lung cancer	Ipilimumab (Yervoy; BMS 734016; MDX 101) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download
Pembrolizumab in combination with lenvatinib for advanced melanoma – first line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Melanoma	Skin Cancer	2021	View \| Download
Pembrolizumab in combination with lenvatinib, platinum chemotherapy, and pemetrexed for non-small cell lung cancer	Chemotherapy , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475) , Pemetrexed (Alimta; pemetrexed ditromethamine dihydrate; pemetrexed ditrometamol; pemetrexed disodium)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download
Pembrolizumab in combination with neoadjuvant chemotherapy and adjuvant endocrine therapy for early-strage breast cancer	Pembrolizumab (Keytruda; MK-3475)	Breast cancer	Breast Cancer	2021	View \| Download
Pembrolizumab in combination with olaparib as maintenance therapy for non-small-cell lung cancer following first line treatment	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download
Pembrolizumab in combination with olaparib for anti-hormone and chemotherapy failure metastatic castration-resistant prostate cancer – third line	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) , Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download