Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Avalglucosidase alfa for late-onset Pompe disease	Avalglucosidase alfa (neoGAA; GZ-402666)	Pompe disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy	Avapritinib (BLU-285; Ayvakit)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2019	View \| Download
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance	Avelumab (Bavencio; MSB-0010718C)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Avelumab in addition to best supportive care for locally advanced or metastatic urothelial cancer	Avelumab (Bavencio; MSB-0010718C)	Bladder cancer	Urological Cancer	2019	View \| Download
Axicabtagene ciloleucel for relapsed/refractory diffuse large B-cell lymphoma – second-line	Axicabtagene Ciloleucel (Yescarta; KTE-C19)	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2019	View \| Download
Axicabtagene ciloleucel for relapsed/refractory indolent non-Hodgkin lymphoma	Axicabtagene Ciloleucel (Yescarta; KTE-C19)	Non-Hodgkin lymphoma (NHL)	Haematological Cancer and Lymphomas	2019	View \| Download
Baricitinib for moderate to severe atopic dermatitis	Baricitinib (LY3009104; Olumiant) , Corticosteroids	Atopic dermatitis	Dermatology	2019	View \| Download
BCX7353 for prevention of acute attacks of angioedema in hereditary angioedema	BCX7353 (Berotralstat; ORLADEYO)	Hereditary angioedema (HAE)	Genetic Disorders , Immunology	2019	View \| Download
Belantamab mafodotin for relapsed / refractory multiple myeloma – Fourth line	Belantamab mafodotin (GSK2857916; anti-BCMA-ADC)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2019	View \| Download
Belimumab for lupus nephritis	Belimumab (Benlysta; Lymphostat-B)	Lupus nephritis	Immunology , Nephrology	2019	View \| Download