Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 200 Results

Title
Intervention Indication Therapeutic Area Year Actions
Apadamtase alfa for treating acute thrombotic thrombocytopenic purpura (TTP) episodes associated with congenital TTP (cTTP) and long-term prophylaxis in patients with congenital ADAMTS-13 deficiency Apadamtase alfa congenital ADAMTS-13 deficiency , Thrombotic thrombocytopenic purpura Haematology 2022 View  |  Download
Amivantamab with chemotherapy for previously untreated advanced EGFR exon 20 insertion mutations positive non-small cell lung cancer Amivantamab (JNJ-6372; JNJ-61186372) , Chemotherapy Non-small-cell lung cancer (NSCLC) Lung and Respiratory Cancer 2022 View  |  Download
Alpelisib and Olaparib for treating platinum-resistant or refractory BRCA wild-type ovarian cancer Alpelisib (BYL719; Piqray) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281) Ovarian cancer Female Reproductive Cancer 2022 View  |  Download
Acalabrutinib with venetoclax for previously untreated chronic lymphocytic leukaemia or small lymphocytic lymphoma Acalabrutinib (Calquence; ACP-196) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199) Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL) Haematological Cancer and Lymphomas 2022 View  |  Download
Acalabrutinib with venetoclax and obinutuzumab for treating previously untreated chronic lymphocytic leukaemia Acalabrutinib (Calquence; ACP-196) , Obinutuzumab (Gazyvaro; RO5072759; GA101; Afutuzumab) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199) Chronic lymphocytic leukaemia (CLL) Haematological Cancer and Lymphomas 2022 View  |  Download
Acalabrutinib with bendamustine and rituximab for treating previously untreated mantle cell lymphoma Acalabrutinib (Calquence; ACP-196) , Bendamustine (Treanda; EP-3102; Levact; Ribomustin; bendamustine hydrochloride monohydrate; bendamustine hydrochloride) , Rituximab (MabThera; Rituxan; RG 105) Mantle cell lymphoma Haematological Cancer and Lymphomas 2022 View  |  Download
ABP 959 for treating paroxysmal nocturnal
haemoglobinuria
ABP 959 Paroxysmal nocturnal haemoglobinuria (PNH) Haematology 2022 View  |  Download
Abemaciclib with abiraterone acetate and prednisone for metastatic castration-resistant prostate cancer Abemaciclib (LY2835219; Verzenio; CC-115) , Abiraterone acetate (Zytiga; Yonsa) , Prednisone (Decadron; Lodotra) Prostate cancer Male Reproductive Cancer 2022 View  |  Download
Abatacept with a calcineurin inhibitor and methotrexate for prophylaxis of acute graft versus host disease Abatacept (Orencia) Graft versus host disease (GvHD) Immunology 2022 View  |  Download
Abatacept for treating idiopathic inflammatory myopathies Abatacept (Orencia) Idiopathic inflammatory myopathies Immunology , Musculoskeletal System 2022 View  |  Download
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