Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Selpercatinib for advanced thyroid cancer with RET alterations	Selpercatinib (LOXO-292; LY3527723)	Medullary thyroid cancer (MTC) , Thyroid cancer	Head and Neck Cancer , Oncology	2019	View \| Download
Selpercatinib for previously untreated medullary thyroid cancer with RET mutation in patients ages 12 and older	Selpercatinib (LOXO-292; LY3527723)	Medullary thyroid cancer (MTC)	Head and Neck Cancer	2022	View \| Download
Tiragolumab with atezolizumab for oesophageal squamous cell cancer	Atezolizumab (Tecentriq; MPDL3280A) , Tiragolumab (RG-6058; MTIG7192A)	Oesophageal squamous cell carcinoma	Head and Neck Cancer	2023	View \| Download
Tislelizumab for oesophageal cancer – second line	Tislelizumab (BGB-A317; BGBA-317)	Oesophageal cancer	Head and Neck Cancer	2021	View \| Download
Tislelizumab in combination with chemotherapy for nasopharyngeal cancer – first line	Cisplatin (Platinol) , Gemcitabine (Gemzar; gemcitabine hydrochloride) , Tislelizumab (BGB-A317; BGBA-317)	Nasopharyngeal cancer	Head and Neck Cancer	2021	View \| Download
Tislelizumab in combination with Paclitaxel, Cisplatin, and Radiotherapy for Oesophageal cancer	Cisplatin (Platinol) , Paclitaxel (Taxol; paclitaxel albumin) , Tislelizumab (BGB-A317; BGBA-317)	Squamous cell carcinoma (SCC)	Head and Neck Cancer	2022	View \| Download
Toripalimab in combination with paclitaxel and cisplatin for treating advanced or metastatic oesophageal squamous cell cancer without previous systemic chemotherapy	Cisplatin (Platinol) , Paclitaxel (Taxol; paclitaxel albumin) , Toripalimab		Head and Neck Cancer	2023	View \| Download
Toripalimab with chemotherapy for previously untreated recurrent or metastatic nasopharyngeal carcinoma	Chemotherapy , Toripalimab	Nasopharyngeal carcinoma	Head and Neck Cancer	2023	View \| Download
Xevinapant with platinum-based chemoradiotherapy for previously untreated locally advanced squamous cell carcinoma of the head and neck	Xevinapant (Debio 1143; AT-406)	Head and neck cancer	Head and Neck Cancer	2022	View \| Download