Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Efgartigimod alfa (subcutaneous injection) for treating generalised myasthenia gravis	Efgartigimod alfa (ARGX-113)	Myasthenia gravis (MG)	Musculoskeletal System	2023	View \| Download
Edasalonexent for Duchene muscular dystrophy	Edasalonexent (CAT-1004)	Duchenne muscular dystrophy (DMD)	Genetic Disorders , Musculoskeletal System	2020	View \| Download
ECCS-50 (Cytori stem cell therapy) for moderate to severe hand dysfunction due to Scleroderma	ECCS-50 (Adipose-derived stem and regenerative cells (ADRCs))	Hand dysfunction	Dermatology , Musculoskeletal System	2017	View \| Download
Dronabinol for muscle spasticity caused by multiple sclerosis	Dronabinol (BX-1; PPP-002; Syndros; Namisol; ECP002A)	Muscle spasticity	Musculoskeletal System , Neurology	2021	View \| Download
Domagrozumab (PF-6252616) for Duchenne muscular dystrophy in children and adolescents	Domagrozumab (PF-06252616)	Duchenne muscular dystrophy (DMD)	Genetic Disorders , Musculoskeletal System	2017	View
Denosumab for the prevention of skeletal related events in patients with multiple myeloma – first line	Denosumab (AMG 162; Prolia; Xgeva)	Prevention of skeletal related events in multiple myeloma	Haematological Cancer and Lymphomas , Musculoskeletal System	2017	View \| Download
Denosumab biosimilar for treating postmenopausal osteoporosis	Denosumab biosimilar	Postmenopausal osteoporosis	Musculoskeletal System	2022	View \| Download
Clostridium botulinum Type A toxin (Dysport) for Spasmodic torticollis	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Spasmodic torticollis	Musculoskeletal System , Neurology	2017	View \| Download
Clostridium botulinum neurotoxin A (Xeomin) for lower limb spasticity due to cerebral palsy – first line	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Lower limb spasticity	Musculoskeletal System , Neurology	2017	View \| Download
Cethrin for traumatic spinal cord injury	Cethrin (BA 210; VX-210)	Spinal cord injury	Musculoskeletal System	2017	View \| Download