Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Upadacitinib for non-radiographic axial spondyloarthritis	Upadacitinib (ABT-494; Rinvoq; upadacitinib hemihydrate)	Axial spondyloarthritis	Rheumatology	2021	View \| Download
Upadacitinib for Adults with Moderate to Severe Active Rheumatoid Arthritis After Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (DMARDs) or Biologic DMARDs Failure	Upadacitinib (ABT-494; Rinvoq; upadacitinib hemihydrate)	Rheumatoid arthritis	Rheumatology	2017	View \| Download
Upadacitinib for active psoriatic arthritis with inadequate response to biological or non-biological DMARDs	Upadacitinib (ABT-494; Rinvoq; upadacitinib hemihydrate)	Psoriatic arthritis	Dermatology , Rheumatology	2019	View \| Download
Tofacitinib for polyarticular juvenile idiopathic arthritis	Tofacitinib citrate (Xeljanz; CP-690550)	Juvenile idiopathic arthritis	Rheumatology	2019	View \| Download
Tocilizumab biosimilar for treating moderate to severe active rheumatoid arthritis	Tocilizumab biosimilar (Avtozma)	Rheumatoid arthritis	Rheumatology	2023	View \| Download
Tocilizumab (RoACTEMRA) [subcutaneous injection with an auto injector device] for adult patients with moderate to severe active rheumatoid arthritis - after DMARD failure	Tocilizumab (Actemra; R1569; RoActemra)	Rheumatoid arthritis	Rheumatology	2017	View \| Download
Tanezumab for moderate to severe chronic pain associated with osteoarthritis and chronic low back pain	Tanezumab (PF-04383119; RN624)	Back pain , Osteoarthritic pain	Musculoskeletal System , Pain Relief , Rheumatology	2019	View \| Download
Subcutaneous Tocilizumab (RoACTEMRA) With or Without Methotrexate for the Treatment of Inadequate Responders in Systemic Juvenile Idiopathic Arthritis	Methotrexate (MTX; Otrexup; Vibex MTX; MQX-5902; methotrexate disodium; methotrexate sodium) , Tocilizumab (Actemra; R1569; RoActemra)	Juvenile idiopathic arthritis	Rheumatology	2017	View \| Download
Secukinumab for Non-Radiographic Axial Spondyloarthritis – second or subsequent line	Secukinumab (Cosentyx; AIN457)	Spondyloarthritis	Musculoskeletal System , Rheumatology	2018	View \| Download
Secukinumab for enthesitis-related arthritis and juvenile psoriatic arthritis in children and adolescents from the age of 2 years	Secukinumab (Cosentyx; AIN457)	Enthesitis-related arthritis , Juvenile psoriatic arthritis	Rheumatology	2019	View \| Download