Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Zanubrutinib for Waldenstrom's Macroglobulinemia	Zanubrutinib (BGB-3111; Brukinsa)	Non-Hodgkin lymphoma (NHL)	Haematological Cancer and Lymphomas	2018	View \| Download
Venetoclax in combination with bortezomib and dexamethasone for relapsed multiple myeloma - second line and beyond	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Venetoclax in combination with a hypomethylating agent or low dose cytarabine for newly diagnosed acute myeloid leukaemia	hypomethylating agent , Low-dose cytarabine , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2018	View \| Download
Veliparib in addition to carboplatin and paclitaxel for epithelial ovarian, fallopian tube, or primary peritoneal cancer	Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin) , Veliparib (ABT-888; NSC 737664)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2018	View \| Download
Ustekinumab for Moderately to Severely Active Ulcerative Colitis	Ustekinumab (Stelara; CNTO 1275; CNTO-1275)	Ulcerative colitis	Gastroenterology	2018	View \| Download
Udenafil for congenital heart disease in adolescents after fontan palliation	Udenafil (Zydena; DA8159; ME-3113; WC-3043; WC-3055)	Congenital heart disease	Cardiovascular System	2018	View \| Download
Ublituximab in Combination with Ibrutinib for High Risk Chronic Lymphocytic Leukaemia	Ibrutinib (Imbruvica) , Ublituximab (TG-1101; LFB-R603)	Chronic lymphocytic leukaemia (CLL)	Haematological Cancer and Lymphomas	2018	View \| Download
Triptorelin Pamoate (subcutaneous injection) for Prostate Cancer	Triptorelin Pamoate (Decapeptyl)	Prostate cancer	Male Reproductive Cancer	2018	View \| Download
Trifluridine and Tipiracil for Metastatic Gastric Cancer – third line and above	Lonsurf; TAS-102 (fixed dose combination: Trifluridine; Tipiracil hydrochloride)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2018	View \| Download
Treosulfan in combination with Fludarabine for Malignant and Non-Malignant diseases - prior to stem cell transplantation	Fludarabine (fludarabine phosphate) , Treosulfan (Ovastat)	Acute myeloid leukaemia (AML) , Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2018	View \| Download