Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Selpercatinib for previously untreated advanced RET fusion-positive non-small cell lung cancer	Selpercatinib (LOXO-292; LY3527723)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download
Setmelanotide for obesity in Bardet-Biedl syndrome and Alstrom syndrome	Setmelanotide (RM-493)	Hyperphagia , Obesity	Endocrine Nutritional and Metabolic Disorders , Gastroenterology , Genetic Disorders	2021	View \| Download
Sintilimab in combination with pemetrexed and platinum chemotherapy for advanced or metastatic non-small cell lung cancer	Carboplatin (Paraplatin) , Pemetrexed (Alimta; pemetrexed ditromethamine dihydrate; pemetrexed ditrometamol; pemetrexed disodium) , Sintilimab (IBI 308; IBI 380; Tyvyt)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download
Sparsentan for treating Focal Segmental Glomerulosclerosis	Sparsentan (RE-021; PS433540)	Focal segmental glomerulosclerosis (FSGS)	Nephrology	2021	View \| Download
Spesolimab for the treatment of acute flares of generalised pustular psoriasis	Spesolimab (BI 655130)	Generalised pustular psoriasis	Dermatology	2021	View \| Download
Talazoparib in addition to enzalutamide for metastatic castration-resistant prostate cancer	Enzalutamide (Xtandi; MDV3100) , Talazoparib (MDV3800; BMN-673; Talzenna; talazoparib tosylate)	Prostate cancer	Male Reproductive Cancer	2021	View \| Download
Tirzepatide for treating type 2 diabetes mellitus	Tirzepatide (LY3298176)	Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2021	View \| Download
Tisagenlecleucel for relapsed or refractory follicular lymphoma	Tisagenlecleucel-T (Kymriah; CTL019)	Follicular lymphoma	Haematological Cancer and Lymphomas	2021	View \| Download
Tisagenlecleucel for treating relapsed or refractory aggressive B-cell non-Hodgkin lymphoma – second line	Tisagenlecleucel-T (Kymriah; CTL019)	B-cell non-Hodgkin lymphoma	Haematological Cancer and Lymphomas	2021	View \| Download
Tislelizumab for advanced non-small cell lung cancer after platinum based chemotherapy	Tislelizumab (BGB-A317; BGBA-317)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2021	View \| Download