Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab in combination with gemcitabine and cisplatin for previously untreated advanced/unresectable biliary tract cancer	Cisplatin (Platinol) , Gemcitabine (Gemzar; gemcitabine hydrochloride) , Pembrolizumab (Keytruda; MK-3475)	Biliary tract cancer	Gastrointestinal Cancer	2021	View \| Download
Pembrolizumab in addition to trastuzumab and chemotherapy for HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma – First-line	Pembrolizumab (Keytruda; MK-3475) , Trastuzumab (Herceptin; RG-597)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Pembrolizumab in addition to chemotherapy for perioperative treatment of gastric or gastro-oesophageal junction adenocarcinoma	FLOT , Pembrolizumab (Keytruda; MK-3475)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2019	View \| Download
Pembrolizumab for Stage IV Colorectal Carcinoma – first line	Pembrolizumab (Keytruda; MK-3475)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2018	View \| Download
Pembrolizumab for Hepatocellular Carcinoma – Adjuvant	Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2021	View \| Download
Pembrolizumab for Advanced Hepatocellular Carcinoma – second line onwards	Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2018	View \| Download
Pembrolizumab (KEYTRUDA) for advanced, metastatic oesophageal cancer – second line	Pembrolizumab (Keytruda; MK-3475)	Gastro-oesophageal junction cancer , Oesophageal cancer	Gastrointestinal Cancer , Head and Neck Cancer	2017	View \| Download
Pembrolizumab (Keytruda) for advanced gastric or gastroesophageal junction adenocarcinoma – first line	Pembrolizumab (Keytruda; MK-3475)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2017	View \| Download
PEGPH20 in addition to Nab-paclitaxel and Gemcitabine for Metastatic Pancreatic Ductal Adenocarcinoma	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , Pegvorhyaluronidase alfa (PEGPH20)	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download
Olaparib for Metastatic Pancreatic Cancer with gBRCA Mutation	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download