Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Carotuximab in combination with Pazopanib for Advanced Angiosarcoma	Carotuximab (TRC105; DE-122) , Pazopanib (Votrient; GW 786034; pazopanib hydrochloride)	Soft tissue sarcoma	Sarcoma	2018	View \| Download
Cenobamate for Partial Focal Epilepsy – Adjunctive Therapy	Cenobamate (YKP3089)	Epilepsy	Neurology	2018	View \| Download
CER-001 for Familial Primary Hypoalphalipoproteinemia	CER-001	Familial primary hypoalphalipoproteinemia	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2018	View \| Download
Crenolanib for Advanced or Metastatic Gastrointestinal Stromal Tumours (GISTs) with the D842V Mutation in the PDGFRA Gene	Crenolanib (CP-868; CP-868596)	Gastrointestinal stromal tumour (GIST)	Gastrointestinal Cancer	2018	View \| Download
Crizotinib (Xalcori) for locally advanced or metastatic Non‐Small Cell Lung Cancer (NSCLC)	Crizotinib (Xalkori; PF-02341066; Xalkor)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2018	View \| Download
Cysteamine bitartrate for cystic fibrosis exacerbations	Cysteamine bitartrate (Procysbi; RP103; Lynovex; NM001; Cystadrops; Mercaptamine)	Cystic fibrosis	Genetic Disorders , Respiratory System	2018	View \| Download
Daratumumab in addition to Bortezomib, Thalidomide and Dexamethasone for newly diagnosed Multiple Myeloma	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Thalidomide (Taldo)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Daratumumab in combination with Bortezomib, Melphalan and Prednisone for Multiple Myeloma – first line	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Melphalan , Prednisone (Decadron; Lodotra)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2018	View \| Download
Darolutamide for Non‐metastatic, Castration-resistant Prostate Cancer	Darolutamide (ODM-201; BAY-1841788; Nubeqa)	Prostate cancer	Male Reproductive Cancer	2018	View \| Download
Depatuxizumab mafodotin for newly diagnosed EGFR‐amplified glioblastoma – first line	Depatuxizumab mafodotin (ABT-414) , Temozolomide (Temodar; Temodal; SCH 52365)	Glioma	Neurological Cancer	2018	View \| Download