Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 145 Results

Title
Intervention Indication Therapeutic Area Year Actions
Elexacaftor/tezacaftor/ivacaftor (fixed-dose combination) for cystic fibrosis heterozygous for F508del mutation and one minimal function mutation in patients aged 6 to 11 years Elexacaftor (VX-445) , Ivacaftor (Kalydeco; VX-770) , Symkevi (fixed dose combination: Tezacaftor; Ivacaftor) Cystic fibrosis Genetic Disorders , Respiratory System 2019 View  |  Download
Elexacaftor/tezacaftor/ivacaftor (fixed-dose combination) for cystic fibrosis homozygous for F508del mutation in patients aged 6 to 11 years old Elexacaftor (VX-445) , Ivacaftor (Kalydeco; VX-770) , Symkevi (fixed dose combination: Tezacaftor; Ivacaftor) Cystic fibrosis Genetic Disorders , Respiratory System 2019 View  |  Download
Encorafenib in combination with binimetinib and cetuximab for BRAF V600E mutant metastatic colorectal cancer Binimetinib (MEK162; MEK-162; ARRY-162) , Cetuximab (Erbitux; STI-001) , Encorafenib (LGX818) Colorectal cancer Gastrointestinal Cancer , Oncology 2019 View  |  Download
Entresto for chronic heart failure with preserved ejection fraction Entresto; LCZ 696 (fixed dose combination: Sacubitril; Valsartan) Heart failure (HF) Cardiovascular System 2019 View  |  Download
Enzalutamide in addition to androgen deprivation therapy for treating metastatic hormone-sensitive prostate cancer Enzalutamide (Xtandi; MDV3100) Prostate cancer Male Reproductive Cancer 2019 View  |  Download
ERC1671 (Gliovac) for recurrent grade IV glioma Bevacizumab (Avastin; R 435; RG 405; RG 435) , ERC1671 (Gliovac) Glioma Neurological Cancer 2019 View  |  Download
Esketamine (nasal spray) for major depressive disorder with imminent risk of suicide Esketamine (JNJ-54135419; Keyzilen; AM-101; esketamine hydrochloride) Major depressive disorder (MDD) Mental and Behavioural Health 2019 View  |  Download
Evinacumab for homozygous familial hypercholesterolemia Evinacumab (REGN1500) Hyperlipidaemia Endocrine Nutritional and Metabolic Disorders 2019 View  |  Download
Fenfluramine hydrochloride for treatment of seizures associated with Lennox-Gastaut syndrome Fenfluramine (Brabafen; ZX008; fenfluramine hydrochloride) Lennox-Gastaut syndrome Neurology 2019 View  |  Download
Fevipiprant maintenance therapy for uncontrolled asthma – add on therapy Fevipiprant (QAW-039) Asthma Respiratory System 2019 View  |  Download
Medicines
Medicine Industry's Gateway to NICE
Support for Industry
Outputs & Publications