Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Zolbetuximab for previously untreated advanced gastric or gastro-oesophageal junction adenocarcinoma	Zolbetuximab (IMAB362)	Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2022	View \| Download
Zanidatamab for treating advanced or metastatic HER2-positive biliary tract cancer in adults	Zanidatamab (ZW-25)	Biliary tract cancer	Gastrointestinal Cancer	2023	View \| Download
Tucatinib with trastuzumab for treating colorectal cancer	Trastuzumab (Herceptin; RG-597) , Tucatinib (ONT-380)	Colorectal cancer	Gastrointestinal Cancer	2022	View \| Download
Trifluridine and Tipiracil for Metastatic Gastric Cancer – third line and above	Lonsurf; TAS-102 (fixed dose combination: Trifluridine; Tipiracil hydrochloride)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2018	View \| Download
Trastuzumab deruxtecan for HER2-positive gastric or gastroesophageal junction adenocarcinoma – third-line	Trastuzumab deruxtecan (DS-8201a; Enhertu)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2021	View \| Download
Tislelizumab with chemotherapy for previously untreated advanced oesophageal squamous cell carcinoma	Tislelizumab (BGB-A317; BGBA-317)	Oesophageal squamous cell carcinoma	Gastrointestinal Cancer	2022	View \| Download
Tislelizumab with chemotherapy for previously untreated unresectable or metastatic gastric cancer or gastro-oesophageal junction adenocarcinoma	Chemotherapy , Tislelizumab (BGB-A317; BGBA-317)	Gastric cancer , Gastro-oesophageal junction adenocarcinoma	Gastrointestinal Cancer	2022	View \| Download
Tislelizumab for treating unresectable, previously untreated hepatocellular carcinoma	Tislelizumab (BGB-A317; BGBA-317)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2022	View \| Download
TAS-102 with bevacizumab for treating refractory metastatic colorectal cancer after 2 previous therapies	Bevacizumab (Avastin; R 435; RG 405; RG 435) , Lonsurf; TAS-102 (fixed dose combination: Trifluridine; Tipiracil hydrochloride)	Colorectal cancer	Gastrointestinal Cancer , Oncology	2023	View \| Download
siG12D‐LODER in addition to standard chemotherapy for locally advanced pancreatic cancer	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , siG12D-LODER	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download