Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 65 Results

Title
Intervention Indication Therapeutic Area Year Actions
Durvalumab in combination with tremelimumab for unresectable hepatocellular carcinoma – first line Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Tremelimumab (CP-675206; CP-675 206) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2019 View  |  Download
Durvalumab in addition to gemcitabine and cisplatin for advanced biliary tract cancer – first line Cisplatin (Platinol) , Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Gemcitabine (Gemzar; gemcitabine hydrochloride) Biliary tract cancer Gastrointestinal Cancer 2021 View  |  Download
Durvalumab for previously untreated,hepatocellular carcinoma Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2021 View  |  Download
Durvalumab and bevacizumab in addition to transarterial chemoembolisation for locoregional hepatocellular carcinoma Bevacizumab (Avastin; R 435; RG 405; RG 435) , Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) , Transarterial Chemoembolisation (TACE) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2021 View  |  Download
Durvalumab adjuvant therapy for treating hepatocellular carcinoma at high risk of recurrence after curative treatment Durvalumab (Imfinzi; MEDI4736; MEDI-4736; MEDI 4736) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2022 View  |  Download
Crenolanib for Advanced or Metastatic Gastrointestinal Stromal Tumours (GISTs) with the D842V Mutation in the PDGFRA Gene Crenolanib (CP-868; CP-868596) Gastrointestinal stromal tumour (GIST) Gastrointestinal Cancer 2018 View  |  Download
Cabozantinib in combination with atezolizumab for advanced hepatocellular carcinoma –first line Atezolizumab (Tecentriq; MPDL3280A) , Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2021 View  |  Download
Cabozantinib for Hepatocellular Carcinoma Cabozantinib (XL-184; Cabometyx; Cometriq; XL 184) Hepatocellular carcinoma (HCC) Gastrointestinal Cancer 2017 View  |  Download
Bintrafusp alfa for locally advanced or metastatic biliary tract cancer – second-line Bintrafusp alfa (M7824; GSK4045154) Biliary tract cancer Gastrointestinal Cancer 2020 View  |  Download
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance Avelumab (Bavencio; MSB-0010718C) Gastric cancer , Gastro-oesophageal junction cancer Gastrointestinal Cancer 2019 View  |  Download
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