Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pembrolizumab with enzalutamide for treating metastatic castration-resistant prostate cancer	Enzalutamide (Xtandi; MDV3100) , Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Pembrolizumab with Enzalutamide and androgen deprivation therapy for the treatment of metastatic hormone sensitive prostate cancer	Androgen deprivation therapy , Enzalutamide (Xtandi; MDV3100) , Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Pembrolizumab with chemoradiotherapy for treating high-risk locally advanced cervical cancer	Chemoradiotherapy , Pembrolizumab (Keytruda; MK-3475)	Cervical cancer	Female Reproductive Cancer	2022	View \| Download
Pembrolizumab perioperative therapy with neoadjuvant chemotherapy for treating cisplatin eligible muscle-invasive bladder cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Bladder cancer	Urological Cancer	2022	View \| Download
Pembrolizumab and chemotherapy with or without radiotherapy as an adjuvant therapy for treating newly diagnosed high-risk endometrial cancer	Chemotherapy , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2022	View \| Download
Pembrolizumab and chemotherapy for resectable nonsmall-cell lung cancer	Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Paclitaxel with Encequidar for advanced breast cancer	Encequidar (HM-30181) , Paclitaxel (Taxol; paclitaxel albumin)	Breast cancer	Breast Cancer	2022	View \| Download
Oxybutynin hydrochloride for treating neurogenic detrusor overactivity	Oxybutynin hydrochloride (Vesoxx)	Neurogenic detrusor overactivity	Neurology , Urology	2022	View \| Download
Otilimab in combination with conventional synthetic DMARDs for treating rheumatoid arthritis	Otilimab	Rheumatoid arthritis	Rheumatology	2022	View \| Download
Osimertinib maintenance therapy for treating stage III unresectable EGFR mutation positive non-small-cell lung cancer after definitive platinum-based chemoradiation therapy	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download