Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Concizumab for treating haemophilia A and haemophilia B	Concizumab (NN-7415; mAb-2021; NNC-0172-0000-2021; NNC-0172-2021; NNC-172-2021)	Haemophilia A , Haemophilia B	Haematology	2022	View \| Download
Crizanlizumab for the prevention of recurrent vaso-occlusive crises in children with sickle cell disease	Crizanlizumab (SEG101; Adakveo)	Sickle cell disease (SCD)	Haematology	2022	View \| Download
Crovalimab for treatment of paroxysmal nocturnal haemoglobinuria	Crovalimab	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
Dabrafenib with trametinib for treating paediatric BRAF V600 mutated high-grade or low-grade glioma	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Glioma	Neurological Cancer	2022	View \| Download
Danicopan with eculizumab or ravulizumab for treating paroxysmal nocturnal haemoglobinuria	Danicopan (ACH-0144471; ACH-4471; ALXN2040) , Ravulizumab (ALXN1210; Ultomiris)	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
Daratumumab for the treating high-risk smouldering multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2022	View \| Download
Daratumumab with bortezomib, lenalidomide and dexamethasone for previously untreated transplant eligible multiple myeloma	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2022	View \| Download
Denosumab biosimilar for treating postmenopausal osteoporosis	Denosumab biosimilar	Postmenopausal osteoporosis	Musculoskeletal System	2022	View \| Download
Dersimelagon for previously untreated erythropoietic protoporphyria and X-linked protoporphyria	Dersimelagon	Erythropoietic protoporphyria , X-linked protoporphyria	Dermatology , Haematology	2022	View \| Download
Dexmedetomidine film for agitation associated with bipolar disorder	Dexmedetomidine	Bipolar disorder	Mental and Behavioural Health	2022	View \| Download