Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Olaparib (Lynparza) tablets for recurrent platinum-sensitive BRCA-mutated ovarian cancer – maintenance therapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2017	View \| Download
Olaparib for BRCA mutated and high risk HER2 negative breast cancer - adjuvant therapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Breast cancer	Breast Cancer	2020	View \| Download
Olaparib for BRCAm or ATM mutated metastatic castration-resistant prostate cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Prostate cancer	Male Reproductive Cancer	2019	View \| Download
Olaparib for Metastatic Pancreatic Cancer with gBRCA Mutation	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Pancreatic cancer	Gastrointestinal Cancer	2018	View \| Download
Olaparib in addition to abiraterone for metastatic castration-resistant prostate cancer – First line	Abiraterone acetate (Zytiga; Yonsa) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Olaparib in combination with bevacizumab for ovarian, fallopian tube or primary peritoneal cancer – maintenance therapy	Bevacizumab (Avastin; R 435; RG 405; RG 435) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Fallopian tube cancer , Ovarian cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Olaparib maintenance therapy for non-gBRCA mutated high-grade serous ovarian cancer after platinum-based chemotherapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Non-gBRCA mutated high-grade serous ovarian cancer	Female Reproductive Cancer	2022	View \| Download
Olaparib monotherapy for BRCA-mutated platinum-sensitive relapsed ovarian, fallopian tube or primary peritoneal cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Oleogel-S10 for Inherited Epidermolysis Bullosa	Oleogel-S10 (Episalvan)	Inherited epidermolysis bullosa (EB)	Dermatology , Genetic Disorders	2018	View \| Download
Olezarsen for treating familial chylomicronaemia syndrome	Olezarsen (ISIS 678354; AKCEA-APOCIII-LRx)	Familial chylomicronaemia syndrome (FCS)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2024	View \| Download