Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 815 Results

Title
Intervention Indication Therapeutic Area Year Actions
Axalimogene Filolisbac for Cervical Cancer – Beyond First Line Treatment Axalimogene filolisbac (ADXS11-001) Cervical cancer Female Reproductive Cancer 2018 View  |  Download
AVXS-101 for spinal muscular atrophy Onasemnogene abeparvovec (Zolgensma; AVXS-101; scAAV9.CB.SMN) Spinal muscular atrophy (SMA) Genetic Disorders , Musculoskeletal System 2018 View  |  Download
Avelumab with or without Pegylated Liposomal Doxorubicin (PLD) for Ovarian Cancer – second line Avelumab (Bavencio; MSB-0010718C) , Pegylated liposomal doxorubicin Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer Female Reproductive Cancer 2018 View  |  Download
Avelumab in combination with axitinib for advanced or metastatic renal cell carcinoma – first line Avelumab (Bavencio; MSB-0010718C) , Axitinib (Inlyta; AG-013736) Renal cell carcinoma (RCC) Renal Cancer 2018 View  |  Download
Avelumab in addition to best supportive care for locally advanced or metastatic urothelial cancer Avelumab (Bavencio; MSB-0010718C) Bladder cancer Urological Cancer 2019 View  |  Download
Avelumab for gastric or gastro-oesophageal junction cancer - first line maintenance Avelumab (Bavencio; MSB-0010718C) Gastric cancer , Gastro-oesophageal junction cancer Gastrointestinal Cancer 2019 View  |  Download
Avelumab for gastric and gastroesophageal junction adenocarcinoma – third line Avelumab (Bavencio; MSB-0010718C) Gastric cancer , Gastro-oesophageal junction cancer Gastrointestinal Cancer 2017 View  |  Download
Avatrombopag in addition to standard of care for chronic immune thrombocytopenia Avatrombopag (Doptelet; E5501; avatrombopag maleate) Immune thrombocytopenia (ITP) Haematology , Immunology 2020 View  |  Download
Avatrombopag for chemotherapy induced thrombocytopenia in patients with nonhaematological cancers Avatrombopag (Doptelet; E5501; avatrombopag maleate) Chemotherapy-induced thrombocytopenia Female Reproductive Cancer , Haematology , Lung and Respiratory Cancer , Toxicology , Urological Cancer 2020 View  |  Download
Avapritinib for unresectable or metastatic gastrointestinal stromal tumours (GIST) who have been treated with at least 3 prior lines of therapy and GIST harbouring the PDGFRA D842V mutation regardless of prior therapy Avapritinib (BLU-285; Ayvakit) Gastrointestinal stromal tumour (GIST) Gastrointestinal Cancer 2019 View  |  Download
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