Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Evinacumab for homozygous familial hypercholesterolemia	Evinacumab (REGN1500)	Hyperlipidaemia	Endocrine Nutritional and Metabolic Disorders	2019	View \| Download
Etrolizumab for treating moderately to severely active ulcerative colitis in adults	Etrolizumab (PRO145223; RG7413; rhuMAb Beta7)	Ulcerative colitis	Gastroenterology	2020	View \| Download
Etrolizumab for Crohn’s Disease	Etrolizumab (PRO145223; RG7413; rhuMAb Beta7)	Crohn's disease	Gastroenterology , Immunology	2021	View \| Download
Etrasimod for treating moderately to severely active ulcerative colitis	Etrasimod (ADP334)	Ulcerative colitis	Gastroenterology	2022	View \| Download
Etranacogene dezaparvovec for treating moderately severe or severe haemophilia B	Etranacogene Dezaparvovec (AMT-061; AAV5-hFIXco-Padua)	Haemophilia B	Haematology	2020	View \| Download
Eszopiclone for treating insomnia	Eszopiclone	Insomnia	Neurology	2024	View \| Download
Estetrol for treating vasomotor symptoms	Estetrol (Donesta; E4)	Hot flushes	Women's Health	2021	View \| Download
Esketamine for Treatment-resistant Depression	Esketamine (JNJ-54135419; Keyzilen; AM-101; esketamine hydrochloride)	Depression	Mental and Behavioural Health	2017	View \| Download
Esketamine (nasal spray) for major depressive disorder with imminent risk of suicide	Esketamine (JNJ-54135419; Keyzilen; AM-101; esketamine hydrochloride)	Major depressive disorder (MDD)	Mental and Behavioural Health	2019	View \| Download
Eryaspase in addition to chemotherapy for treating advanced or metastatic pancreatic cancer – second-line	Eryaspase (Graspa; ERY001) , FOLFOX4 , Gemcitabine (Gemzar; gemcitabine hydrochloride)	Pancreatic cancer	Gastrointestinal Cancer	2020	View \| Download