Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 1152 Results

Clear All Filters

Title	Intervention	Indication	Therapeutic Area	Year	Actions
Pevonedistat in addition to azacitidine for Higher-Risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia and Low Blast Acute Myeloid Leukemia – first-line	Azacitidine (Vidaza; CC-486) , Pevonedistat (MLN-4924; TAK-924)	Acute myeloid leukaemia (AML) , Chronic myelomonocytic leukaemia (CMML) , Myelodysplastic syndrome (MDS)	Haematological Cancer and Lymphomas	2020	View \| Download
Pexastimogene devacirepvec (pexa-vec) for hepatocellular carcinoma – first line	Pexastimogene devacirepvec (Pexa-vec; JX-594)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2017	View \| Download
Pexidartinib for tenosynovial giant cell tumour	Pexidartinib (PLX3397)	Tenosynovial giant cell tumour (TGCT)	Oncology	2019	View \| Download
Phelinun for reduced intensity conditioning treatment prior to allogeneic haematopoietic stem cell transplantation	Melphalan hydrochloride (Cydex; CDX-353; Phelinun)	Acute myeloid leukaemia (AML) , Hodgkin lymphoma , Multiple myeloma (MM) , Neuroblastoma , Non-Hodgkin lymphoma (NHL) , Ovarian cancer	Female Reproductive Cancer , Haematological Cancer and Lymphomas , Neurological Cancer	2021	View \| Download
Pioglitazone for sudden sensorineural hearing loss	Pioglitazone (Actos; AD-4833; pioglitazone hydrochloride)	Sudden sensorineural hearing loss	Ear Nose and Throat (ENT) , Neurology	2019	View \| Download
Pirtobrutinib for chronic lymphocytic leukaemia or small lymphocytic lymphoma after BTK inhibitor therapy	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pirtobrutinib for mantle cell lymphoma	Pirtobrutinib (LY3527727; LOXO-305)	Mantle cell lymphoma	Haematological Cancer and Lymphomas	2021	View \| Download
Pirtobrutinib for untreated chronic lymphocytic leukaemia or small lymphocytic lymphoma	Pirtobrutinib (LY3527727; LOXO-305)	Chronic lymphocytic leukaemia (CLL) , Small lymphocytic lymphoma (SLL)	Haematological Cancer and Lymphomas	2023	View \| Download
Pitolisant for treating narcolepsy in children and adolescents	Pitolisant (Wakix;BF 2649)	Narcolepsy	Neurology	2023	View \| Download
Plinabulin in addition to docetaxel for advanced, metastatic non-small-cell lung cancer - second line or greater	Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Plinabulin (BPI-2358)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2020	View \| Download