Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Insulin icodec for treating Type 1 and Type 2 diabetes	Insulin icodec	Type 1 diabetes , Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2022	View \| Download
Iptacopan for paroxysmal nocturnal haemoglobinuria	Iptacopan	Paroxysmal nocturnal haemoglobinuria (PNH)	Haematology	2022	View \| Download
Ivosidenib for previously treated advanced cholangiocarcinoma	Ivosidenib (Tibsovo; AG-120)	Cholangiocarcinoma	Gastrointestinal Cancer	2022	View \| Download
Ivosidenib with azacitidine for previously untreated acute myeloid leukaemia with an IDH1 mutation	Azacitidine (Vidaza; CC-486) , Ivosidenib (Tibsovo; AG-120)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2022	View \| Download
Kaftrio (Elexacaftor/tezacaftor/ivacaftor) and ivacaftor for treating cystic fibrosis in children (2 to 5 years) with at least one F508del mutation in the CFTR gene	Kaftrio (fixed dose combination: Elexacaftor; Tezacaftor; Ivacaftor)	Cystic fibrosis	Genetic Disorders , Respiratory System	2022	View \| Download
Lazertinib with amivantamab and platinum-based chemotherapy for EGFR-mutated locally advanced or metastatic non-small-cell lung cancer after osimertinib failure	Amivantamab (JNJ-6372; JNJ-61186372) , Lazertinib , Platinum-based chemotherapy	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download
Lenacapavir with optimised background regimen for treating multidrug resistant human immunodeficiency virus (HIV)-1 infection in people aged 12 years and older	Lenacapavir (GS-6207)	HIV-1 infection	Infectious Disease	2022	View \| Download
Leniolisib for previously untreated activated phosphoinositide 3-kinase delta syndrome	Leniolisib	Activated PI3K delta syndrome	Genetic Disorders	2022	View \| Download
Lenvatinib and pembrolizumab with transarterial chemoembolisation for treating hepatocellular carcinoma	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2022	View \| Download
Lenvatinib with pembrolizumab for previously treated metastatic non-small cell lung cancer	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2022	View \| Download