Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Plinabulin in combination with G-CSF for chemotherapy-induced neutropenia	Plinabulin (BPI-2358)	Chemotherapy-induced neutropenia	Immunology , Toxicology	2020	View \| Download
PLX-PAD for Critical Limb Ischaemia (with minor tissue loss) in Patients Unsuitable for Revascularisation	PLX-PAD	Critical limb ischaemia (CLI)	Cardiovascular System	2018	View \| Download
PLX-PAD for injured gluteal musculature following arthroplasty	PLX-PAD	Injured gluteal musculature	Musculoskeletal System	2021	View \| Download
Polatuzumab vedotin in addition to R-CHP for diffuse large B-cell lymphoma – first line	Chemotherapy , Polatuzumab vedotin (DCDS4501A; RG7596; RG-7596; Polivy)	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2020	View \| Download
Polatuzumab vedotin in combination with rituximab and bendamustine for the treatment of diffuse large B-cell lymphoma	Bendamustine (Treanda; EP-3102; Levact; Ribomustin; bendamustine hydrochloride monohydrate; bendamustine hydrochloride) , Polatuzumab vedotin (DCDS4501A; RG7596; RG-7596; Polivy) , Rituximab (MabThera; Rituxan; RG 105)	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2018	View \| Download
Pomalidomide (Imnovid) with bortezomib and dexamethasone for relapsed or refractory multiple myeloma‐ second line and beyond	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Pomalidomide (Imnovid; CC-4047; Pomalyst)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download
Ponatinib for chronic myeloid leukaemia in paediatric patients	Ponatinib (AP24534)	Chronic myeloid leukaemia (CML)	Haematological Cancer and Lymphomas	2024	View \| Download
Ponesimod for Relapsing-remitting Multiple Sclerosis	Ponesimod (ACT-128800; RG-3477)	Multiple sclerosis (MS)	Neurology	2017	View \| Download
Potassium citrate and potassium bicarbonate for distal renal tubular acidosis – first line	Sibnayal (ADV 7103) (fixed dose combination: Potassium bicarbonate; Potassium citrate)	Distal renal tubular acidosis	Endocrine Nutritional and Metabolic Disorders , Nephrology	2020	View \| Download
Potassium citrate-potassium bicarbonate prolonged release granules for treating cystinuria	Potassium citrate-potassium bicarbonate	Cystinuria	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders , Nephrology	2022	View \| Download