Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Darolutamide in addition to docetaxel and androgen deprivation therapy for metastatic hormone-sensitive prostate cancer	Darolutamide (ODM-201; BAY-1841788; Nubeqa) , Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous)	Prostate cancer	Male Reproductive Cancer	2021	View \| Download
Darolutamide with androgen deprivation therapy for metastatic hormone sensitive prostate cancer	Darolutamide (ODM-201; BAY-1841788; Nubeqa)	Prostate cancer	Male Reproductive Cancer	2024	View \| Download
Degarelix acetate prior to or with radiotherapy for prostate cancer	Degarelix acetate , Radiotherapy	Prostate cancer	Male Reproductive Cancer	2023	View \| Download
Enzalutamide (Xtandi) for non-metastatic prostate cancer	Enzalutamide (Xtandi; MDV3100)	Prostate cancer	Male Reproductive Cancer	2017	View \| Download
Enzalutamide in addition to androgen deprivation therapy for treating metastatic hormone-sensitive prostate cancer	Enzalutamide (Xtandi; MDV3100)	Prostate cancer	Male Reproductive Cancer	2019	View \| Download
Ipatasertib in combination with abiraterone and prednisone for metastatic castrate resistant prostate cancer – first line	Abiraterone acetate (Zytiga; Yonsa) , Ipatasertib (GDC-0068; RG7440) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Niraparib for metastatic castration-resistant prostate cancer with DNA-repair anomalies	Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Niraparib with abiraterone acetate and prednisone for metastatic castration resistant prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2022	View \| Download
Niraparib with abiraterone acetate and prednisone for treating homologous recombination repair-mutated metastatic castration-sensitive prostate cancer	Abiraterone acetate (Zytiga; Yonsa) , Niraparib (Zejula; MK 4827; JNJ 64091742; GSK 3985771; niraparib tosylate monohydrate) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2024	View \| Download
Nivolumab in combination with rucaparib for chemotherapy naive metastatic castration-resistant prostate cancer	Docetaxel (Taxotere; docetaxel trihydrate; docetaxel anhydrous) , Enzalutamide (Xtandi; MDV3100) , Nivolumab (Opdivo; BMS-936558; ONO-4538) , Rucaparib (Rubraca; PF-1367338)	Prostate cancer	Male Reproductive Cancer	2019	View \| Download