featured image

Research

Our work is focused around medical devices, diagnostics and digital innovations and our research interest is divided into five broad themes. The themes are open-ended and overlapping, and allow us to deliver ambitious and impactful research  

  • Diagnostics and Prognostics 
  • Digital Health 
  • Medical Technologies and Environmental Challenges  
  • Regulatory Science and Innovation in Healthcare 
  • Horizon Scanning Tools and Methodologies 

Our research projects include short components undertaken by our staff, as well as independent undergraduate and postgraduate projects (including MSc/PhD) conducted throughout the year.  

If you're interested in undertaking research with us (including those looking to undertake PhDs in this area), please contact us at info@io.nihr.ac.uk.

Latest Outputs

Output

The performance of FIT-based and other risk prediction models for colorectal neoplasia in symptomatic patients: a systematic review

The performance of FIT-based and other risk prediction models for colorectal neoplasia in symptomatic patients: a systematic review

Background Colorectal cancer (CRC) incidence and mortality are increasing internationally. Endoscopy services are under significant pressure with many overwhelmed. Faecal immunochemical testing (FIT) has been advocated to identify a high-risk population of symptomatic patients requiring definitive investigation by colonoscopy. Combining FIT with other factors in a risk prediction model could further improve performance in identifying […]

Visit Website
Output

Horizon Scanning Final Report: Identification of Respiratory Tract Infection Technologies 

Horizon Scanning Final Report: Identification of Respiratory Tract Infection Technologies 

Following a request from the AMR Programme Board and the AMR Diagnostic Programme Board, the Innovation Observatory sought to undertake horizon scanning activities for Respiratory Tract Infection (RTI) technologies and to identify the pipeline of development, key players, opportunities and challenges in the field. The findings of that horizon scan were summarised into the accompanying […]

Download
Output

Horizon Scanning Final Report: Identification of Acute deterioration / Sepsis Technologies 

Horizon Scanning Final Report: Identification of Acute deterioration / Sepsis Technologies 

Studies show that a significant number of sepsis patients (20-30%) receive inappropriate antibiotics, and that blood culture testing – the ‘gold standard’ for sepsis diagnosis – varies significantly across healthcare practices. Such variation causes delay in critical test results, and there is additional evidence to suggest that blood culture testing may not influence a change […]

Download
Output

Horizon Scanning Final Report: Identification of Surgical Site Infection Technologies 

Horizon Scanning Final Report: Identification of Surgical Site Infection Technologies 

In this report, the Innovation Observatory has provided a horizon scan of MedTech innovations with the potential to reduce demand for antimicrobials through SSI detection and monitoring. This landscape aims to allow the NHSE & I’s AMR Programme Board to evaluate the potential impact of these SSI innovations and to identify promising technologies for use […]

Download
Output

COVID-19 Impact on Diagnostic Innovations: Emerging Trends and Implications

COVID-19 Impact on Diagnostic Innovations: Emerging Trends and Implications

Diagnostic testing remains the backbone of the coronavirus disease 2019 (COVID-19) response, supporting containment efforts to mitigate the outbreak. The severity of this crisis and increasing capacity issues associated with polymerase chain reaction (PCR)-based testing, accelerated the development of diagnostic solutions to meet demands for mass testing. Since March 2020, the Innovation Observatory has applied […]

Visit Website
Output

Identification of COVID-19 Diagnostics Using Horizon Scanning Approaches to Inform Decision Making

Identification of COVID-19 Diagnostics Using Horizon Scanning Approaches to Inform Decision Making

In response to the COVID-19 pandemic the Innovation Observatory has collated a comprehensive global dataset of SARS-CoV-2 diagnostic tests, supporting stakeholder in assessing priorities and mitigation options in response to testing challenges. Using manual and automated horizon scanning approaches, our diagnostic landscape has provided key insights into the evolution of technological innovations, their regulation and […]

Download
Output

Rapid Technology Scan: Radioligand Technologies

Rapid Technology Scan: Radioligand Technologies

The Innovation Observatory performed a scan of radioligand technologies (imaging and therapeutic) in May 2021, using robust horizon scanning methods to identify promising innovations and to anticipate technological trends. We developed a detailed dataset of technologies by formulating search strategies for radioligand, based on a comprehensive list of terms and input from expert panels. Primary […]

Download
Medicines
Medicine Industry's Gateway to NICE
Support for Industry
Outputs & Publications