Degarelix acetate is approved for the treatment of advanced hormone dependant prostate cancer and treatment of high risk localised or locally advanced prostate cancer, in combination with or prior to radiotherapy. Prostate cancer is a cancer of the prostate gland (a small organ in a man’s pelvis) and is the most common cancer in men […]
Pembrolizumab-vibostolimab is in development for treatment-naïve patients with metastatic non-small cell lung cancer (NSCLC). A metastatic NSCLC is an advanced stage of NSCLC (stage 4), where the cancer has spread from the lungs. NSCLC is the most common form of lung cancer, accounting for about 80 to 85 out of every 100 lung cancer cases. […]
Sacituzumab govitecan is in development for advanced or metastatic non-small cell lung cancer (NSCLC), that has progressed on or after previous therapies with platinum-based chemotherapy and immunotherapy. NSCLC is the most common type of lung cancer accounting for 80-85% of lung cancers. Most common symptoms include a cough, recurrent chest infections, coughing up blood, tiredness […]
Durvalumab in combination with chemotherapy is in clinical development for the treatment of resectable gastric cancer and gastro-oesophageal junction (GEJ) adenocarcinoma. Gastric cancers and GEJ adenocarcinoma are cancers that form in the inner lining of the stomach or where the stomach and the oesophagus meet. Risk factors of these cancers include obesity, older age, gastro-oesophageal […]
Imlunestrant with or without abemaciclib is in development for the treatment of patients with locally advanced or metastatic oestrogen receptor positive (ER+) and human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Breast cancer is when abnormal cells in the breast begin to grow in an uncontrolled way and eventually form a tumour. Locally advanced […]
Selumetinib is currently in clinical development for the treatment of symptomatic and inoperable plexiform neurofibromas associated with type 1 neurofibromatosis in adults. Neurofibromatosis type 1 (NF1), caused by changes in NF1 gene, is a type of genetic disorders that primarily affects the cell growth of neural substance. Due to these changes, the gene is unable […]
Cabozantinib in combination with atezolizumab is in clinical development for the treatment of cancer thatstarted in the prostate, has spread to another part of the body (metastatic), and no longer responds tohormone treatment options (castration-resistant). The prostate is a small gland in a man’s pelvis and isinvolved in the male reproductive system. Symptoms of prostate […]
Topical rapamycin cream is in clinical development for the treatment of facial angiofibroma (FA) associated with tuberous sclerosis complex (TSC). TSC is a rare genetic disorder that affects genes that regulate cell growth. TSC is often associated with FA, which are pinkish or reddish bumps usually located on the cheeks, nose and chin. Although FAs […]
TransCon PTH is in clinical development for the treatment of hypoparathyroidism (HP). HP can be caused when the parathyroid glands do not produce enough parathyroid hormone (PTH). This causes low blood calcium levels (hypocalcaemia). The parathyroid glands are very small glands situated in the neck just behind the thyroid gland and they control calcium levels […]
Garadacimab is in clinical development for preventing attacks in people with hereditary angioedema (HAE). HAE is a rare and potentially life-threating type of angioedema, a condition that causes sudden swelling. There are two types of HAE. Type I is more common and occurs because the body has abnormally low levels of proteins that help regulate […]
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