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Pipeline Analysis

Our Pipeline Analysis offers important and immediate intelligence about the future of health technology within a disease or condition. Underpinned by robust horizon scanning methodology, at the core of our pipeline analysis are an analysis of trends in clinical development that allows for the examination of both their cause and potential impact on healthcare systems. Our methods are reproducible and address clinically relevant questions. Our outputs can be used to steer development reports, inform gaps in ongoing research, address unmet needs, and prepare healthcare systems for upcoming waves of technological innovation. 

Latest Outputs

Output

Horizon Scanning Final Report: Identification of Acute deterioration / Sepsis Technologies 

Horizon Scanning Final Report: Identification of Acute deterioration / Sepsis Technologies 

Studies show that a significant number of sepsis patients (20-30%) receive inappropriate antibiotics, and that blood culture testing – the ‘gold standard’ for sepsis diagnosis – varies significantly across healthcare practices. Such variation causes delay in critical test results, and there is additional evidence to suggest that blood culture testing may not influence a change […]

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Output

Horizon Scanning Final Report: Identification of Surgical Site Infection Technologies 

Horizon Scanning Final Report: Identification of Surgical Site Infection Technologies 

In this report, the Innovation Observatory has provided a horizon scan of MedTech innovations with the potential to reduce demand for antimicrobials through SSI detection and monitoring. This landscape aims to allow the NHSE & I’s AMR Programme Board to evaluate the potential impact of these SSI innovations and to identify promising technologies for use […]

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Output

Horizon Scanning Report: Identification of Urinary Tract Infection Technologies 

Horizon Scanning Report: Identification of Urinary Tract Infection Technologies 

There is a globally recognised need for point-of-care testing and rapid identification of UTIs. Current ‘gold standard’ urine culture diagnostics take hours to yield results, and there remains an unmet need for accurate diagnostics within the elderly population, where UTIs are common and diagnosis is particularly complex. Moreover, evidence raises concerns about the certainty of […]

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Output

Horizon Scanning Final Report: Identification of Respiratory Tract Infection Technologies 

Horizon Scanning Final Report: Identification of Respiratory Tract Infection Technologies 

Following a request from the AMR Programme Board and the AMR Diagnostic Programme Board, the Innovation Observatory sought to undertake horizon scanning activities for Respiratory Tract Infection (RTI) technologies and to identify the pipeline of development, key players, opportunities and challenges in the field. The findings of that horizon scan were summarised into the accompanying […]

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Output

Rapid Technology Scan: Polygenic Risk Scores

Rapid Technology Scan: Polygenic Risk Scores

The Innovation Observatory performed a scan of PRS in March 2021, using robust horizon scanning methods to identify promising innovations and to anticipate technological trends. We developed a detailed dataset of technologies by formulating search strategies for PRS, based on a comprehensive list of terms and input from expert panels. Primary and secondary sources were […]

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Output

Rapid Technology Scan: Radioligand Technologies

Rapid Technology Scan: Radioligand Technologies

The Innovation Observatory performed a scan of radioligand technologies (imaging and therapeutic) in May 2021, using robust horizon scanning methods to identify promising innovations and to anticipate technological trends. We developed a detailed dataset of technologies by formulating search strategies for radioligand, based on a comprehensive list of terms and input from expert panels. Primary […]

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Output

Rapid Technology Scan: Polygenic Risk Scores

Rapid Technology Scan: Polygenic Risk Scores

The Innovation Observatory performed a scan of PRS in March 2021, using robust horizon scanning methods to identify promising innovations and to anticipate technological trends. We developed a detailed dataset of technologies by formulating search strategies for PRS, based on a comprehensive list of terms and input from expert panels. Primary and secondary sources were […]

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Output

Horizon Scan for Histology Independent Technologies

Horizon Scan for Histology Independent Technologies

Histology-Independent Therapies (HITs) for cancer, or Tumour-Agnostic Therapies are recent innovations in oncology wherein treatment is based on the cancer’s genetic and molecular alterations rather than cancer type and/or site of origin.

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