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Rapid Technology Scan: Polygenic Risk Scores

Post Type: Report
Technology Category: Diagnostics
Year: 2021

The Innovation Observatory performed a scan of PRS in March 2021, using robust horizon scanning methods to identify promising innovations and to anticipate technological trends. We developed a detailed dataset of technologies by formulating search strategies for PRS, based on a comprehensive list of terms and input from expert panels.

Primary and secondary sources were systematically scanned using a combination of traditional scanning methods, automated and novel AI/machine learning techniques. Sources included clinical trial registries, MedTech news, academic sources, funding agencies, commercial sites and regulatory authorities.

Together the insights provide a comprehensive landscape to allow decision-makers and HTAs to consider the clinical, financial, infrastructural and logistical provisions to improve preparedness for the potential adoption of these future innovations.