Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
NY-ESO-1 T cells for the treatment of synovial sarcoma	NY-ESO-1c259-modified SPEAR T Cells (GSK3377794)	Soft tissue sarcoma	Sarcoma	2017	View \| Download
Olaparib (Lynparza) tablets for recurrent platinum-sensitive BRCA-mutated ovarian cancer – maintenance therapy	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2017	View \| Download
Osimertinib (Tagrisso) for locally advanced or metastatic non-small cell lung cancer, EGFR mutation positive (Ex19del or L858R) - first line	Osimertinib (Tagrisso; AZD9291; osimertinib mesylate)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2017	View \| Download
Pembrolizumab (Keytruda) for advanced gastric or gastroesophageal junction adenocarcinoma – first line	Pembrolizumab (Keytruda; MK-3475)	Gastric cancer , Gastro-oesophageal junction cancer	Gastrointestinal Cancer	2017	View \| Download
Pembrolizumab (KEYTRUDA) for advanced, metastatic oesophageal cancer – second line	Pembrolizumab (Keytruda; MK-3475)	Gastro-oesophageal junction cancer , Oesophageal cancer	Gastrointestinal Cancer , Head and Neck Cancer	2017	View \| Download
Pembrolizumab (Keytruda) for metastatic castration‐resistant prostate	Pembrolizumab (Keytruda; MK-3475)	Prostate cancer	Male Reproductive Cancer	2017	View \| Download
Pembrolizumab (Keytruda) for non‐small cell lung cancer - first line, previously untreated	Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2017	View \| Download
Pembrolizumab (Keytruda) for triple negative breast cancer	Pembrolizumab (Keytruda; MK-3475)	Breast cancer	Breast Cancer	2017	View \| Download
Pembrolizumab (KEYTRUDA) in combination with carboplatin-paclitaxel/Nab-paclitaxel for metastatic squamous non small cell lung cancer, first line	Carboplatin (Paraplatin) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , Paclitaxel (Taxol; paclitaxel albumin) , Pembrolizumab (Keytruda; MK-3475)	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2017	View \| Download
Pentosan polysulfate sodium (Elmiron) for bladder pain syndrome (interstitial cystitis)	Pentosan polysulphate sodium (Elmiron; AK-150)	Bladder pain syndrome , Interstitial cystitis , Painful bladder syndrome	Nephrology , Urology	2017	View \| Download