Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Obeticholic acid for non-alcoholic steatohepatitis and fibrosis	Obeticholic Acid (Ocaliva; INT-747)	Non-alcoholic steatohepatitis (NASH)	Hepatology	2019	View \| Download
Ofatumumab for relapsing multiple sclerosis	Ofatumumab (Arzerra)	Multiple sclerosis (MS)	Neurology	2019	View \| Download
Olaparib for BRCAm or ATM mutated metastatic castration-resistant prostate cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Prostate cancer	Male Reproductive Cancer	2019	View \| Download
Olaparib in combination with bevacizumab for ovarian, fallopian tube or primary peritoneal cancer – maintenance therapy	Bevacizumab (Avastin; R 435; RG 405; RG 435) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Fallopian tube cancer , Ovarian cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Olaparib monotherapy for BRCA-mutated platinum-sensitive relapsed ovarian, fallopian tube or primary peritoneal cancer	Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Omalizumab for chronic rhinosinusitis with nasal polyps	Omalizumab (Xolair)	Rhinosinusitis	Ear Nose and Throat (ENT)	2019	View \| Download
Onfekafusp alfa in addition to doxorubicin for advanced or metastatic soft tissue sarcoma – first line	Doxorubicin (Livatag; BA-003; Caelyx; Sarcodoxome; SP-1049C; Resmycin; JNS002; doxorubicin hydrochloride) , Onfekafusp alfa (L19-TNF; Fibromun)	Soft tissue sarcoma	Sarcoma	2019	View \| Download
OTL-200 for Metachromatic Leukodystrophy	OTL-200 (GSK-2696274)	Metachromatic leukodystrophy (MLD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders	2019	View \| Download
Palovarotene for episodic and chronic use in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download
Palovarotene for flare-ups in fibrodysplasia ossificans progressiva – first line	Palovarotene (RG-667)	Fibrodysplasia ossificans progressiva	Musculoskeletal System	2019	View \| Download