ADV7103 is currently in clinical development for the treatment of cystinuria in patients aged 1 year and above. Cystinuria is an inherited metabolic condition where irregular changes to genes called SLC3A1 and SLC7A9 results in abnormal transport of the amino acid, cysteine, in the kidney. This results in excessive amounts of cysteine excreted in the urine which does not dissolve. This leads to symptoms like sharp lower back pain, blood in urine, obstruction or infection in urinary tracts and development of kidney stones. There is currently no cure for cystinuria and no approved drugs.
Potassium citrate-potassium bicarbonate prolonged release granules for treating cystinuria
ADV7103 is currently in clinical development for the treatment of cystinuria in patients aged 1 year and above.