Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Zolbetuximab with nab-paclitaxel and gemcitabine for previously untreated metastatic CLDN18.2-positive pancreatic adenocarcinoma	Gemcitabine (Gemzar; gemcitabine hydrochloride) , Nab-Paclitaxel (Abraxane; ABI 007; ABI-007) , Zolbetuximab (IMAB362)	Pancreatic cancer	Gastrointestinal Cancer	2024	View \| Download
Zavegepant for treating acute migraine	Zavegepant (BHV-3500)	Migraine	Neurology	2024	View \| Download
Vutrisiran for treating transthyretin amyloidosis with cardiomyopathy	Vutrisiran (ALN-TTRSC02)	Transthyretin amyloid cardiomyopathy	Cardiovascular System	2024	View \| Download
Vosoritide for treating achondroplasia in children	Vosoritide (BMN 111)	Achondroplasia	Musculoskeletal System	2024	View \| Download
Troriluzole for spinocerebellar ataxia	Troriluzole	Spinocerebellar ataxia	Genetic Disorders , Neurology	2024	View \| Download
Teprotumumab for thyroid eye disease	Teprotumumab ((HZN-001; R-1507; RV 001)	Thyroid eye disease (TED)	Immunology	2024	View \| Download
Telmisartan-amlodipine-indapamide for treating hypertension	Telmisartan-Amlodipine-Indapamide (GMRx2)	Hypertension	Cardiovascular System	2024	View \| Download
Talazoparib with enzalutamide for previously untreated homologous recombination repair-mutated metastatic hormonal-sensitive prostate cancer	Enzalutamide (Xtandi; MDV3100) , Talazoparib (MDV3800; BMN-673; Talzenna; talazoparib tosylate)	Prostate cancer	Male Reproductive Cancer	2024	View \| Download
Setmelanotide for treating acquired hypothalamic obesity in people 4 years and older	Setmelanotide (RM-493)	Hypothalamic obesity	Endocrine Nutritional and Metabolic Disorders	2024	View \| Download
Secukinumab biosimilar for treating plaque psoriasis	Secukinumab biosimilar (BAT2306)	Plaque psoriasis	Dermatology	2024	View \| Download