Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Acoramidis for symptomatic transthyretin amyloid cardiomyopathy	Acoramidis (AG10)	Transthyretin amyloid cardiomyopathy	Cardiovascular System	2023	View \| Download
Angiotensin II acetate (Giapreza) for vasopressor resistant hypotension due to distributive shock	Angiotensin II acetate (Giapreza; LJPC-501)	Orthostatic hypotension	Cardiovascular System	2018	View \| Download
Apabetalone in addition to high-intensity statin therapy for preventing major adverse cardiac events in high-risk cardiovascular disease patients with type 2 diabetes mellitus	Apabetalone (RVX-208)	Major adverse cardiovascular events (MACE)	Cardiovascular System , Endocrine Nutritional and Metabolic Disorders	2018	View \| Download
Aprocitentan for treating resistant hypertension	Aprocitentan (ACT-132577; AC-080; ACT 13257; Actelion)	Resistant hypertension	Cardiovascular System	2023	View \| Download
Avacopan in addition to standard of care for ANCA-associated vasculitis	Avacopan (CCX168)	Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)	Cardiovascular System , Immunology	2018	View \| Download
Benralizumab for treating relapsing or refractory eosinophilic granulomatosis with polyangiitis	Benralizumab (Fasenra; MEDI563)	Eosinophilic granulomatosis with polyangiitis	Cardiovascular System , Immunology	2022	View \| Download
Beraprost modified release in addition to treprostinil for pulmonary arterial hypertension	Esuberaprost (Beraprost-314d; BPS-314d-MR) , Treprostinil (Tyvaso; LIQ861; Orenitram; UT-15C; Remodulin; treprostinil sodium)	Pulmonary arterial hypertension (PAH)	Cardiovascular System , Respiratory System	2018	View \| Download
Canakinumab (ILARIS) for Cardiovascular risk reduction – Add on therapy	Canakinumab (Ilaris; ACZ885)	Cardiovascular disease (CVD)	Cardiovascular System	2017	View \| Download
Dabigatran Etexilate (Pradaxa) for Secondary Stroke Prevention in Patients with Embolic Stroke of Undetermined Source – First Line	Dabigatran etexilate (Pradaxa)	Ischaemic stroke	Cardiovascular System	2017	View \| Download
Dapagliflozin for chronic heart failure with reduced ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download