Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Alpelisib for treating PIK3CA-related overgrowth spectrum	Alpelisib (BYL719; Piqray)	PIK3CA-related overgrowth spectrum (PROS)	Genetic Disorders	2023	View \| Download
Amivantamab with lazertinib for previously untreated locally advanced or metastatic non-small-cell lung cancer	Amivantamab (JNJ-6372; JNJ-61186372) , Lazertinib	Non-small-cell lung cancer (NSCLC)	Lung and Respiratory Cancer	2023	View \| Download
Atezolizumab with paclitaxel and carboplatin for previously untreated advanced endometrial cancer	Atezolizumab (Tecentriq; MPDL3280A) , Carboplatin (Paraplatin) , Paclitaxel (Taxol; paclitaxel albumin)	Endometrial cancer	Female Reproductive Cancer	2023	View \| Download
Basal Insulin-Fc for treating type 1 diabetes	Basal Insulin-Fc	Type 1 diabetes	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Basal Insulin-Fc for type 2 diabetes mellitus	Basal Insulin-Fc	Type 2 diabetes	Endocrine Nutritional and Metabolic Disorders	2023	View \| Download
Botaretigene sparoparvovec for treating X-linked retinitis pigmentosa	Botaretigene sparoparvovec	Retinitis pigmentosa	Ophthalmology	2023	View \| Download
Cabotegravir (long-acting injection) for prevention of HIV-1 infection	Cabotegravir (GSK1265744)	HIV-1 infection	Infectious Disease	2023	View \| Download
Cladribine for treating relapsing-remitting multiple sclerosis	Cladribine	Multiple sclerosis (MS)	Neurology	2023	View \| Download
Dabrafenib with trametinib for treating metastatic or unresectable BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download
Dabrafenib with Trametinib with adjuvant therapy for treating advanced BRAF V600 mutation-positive melanoma in adolescents	Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide)	Melanoma	Skin Cancer	2023	View \| Download