Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Leronlimab in addition to antiretroviral therapy for treatment experienced adult HIV-1 patients	Antiretroviral therapy (ART) , Leronlimab (PRO-140)	HIV-1 infection	Infectious Disease	2021	View \| Download
Lenvatinib in combination with pembrolizumab for advanced/unresectable hepatocellular carcinoma – first-line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Hepatocellular carcinoma (HCC)	Gastrointestinal Cancer	2021	View \| Download
Lenvatinib in combination with Pembrolizumab for advanced or recurrent endometrial cancer - First Line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2021	View \| Download
Lecanemab for treating early Alzheimer's disease	Lecanemab (BAN2401)	Alzheimer's disease	Neurology	2021	View \| Download
Lebrikizumab for moderate to severe atopic dermatitis	Lebrikizumab (TNX-650; LY3650150)	Atopic dermatitis	Dermatology	2021	View \| Download
LAM-561 in addition to radiation therapy and temozolomide for glioblastoma –adjuvant	2-hydroxyoleic acid (2-OHOA; LP561A1; LAM561) , Radiotherapy , Temozolomide (Temodar; Temodal; SCH 52365)	Glioma	Neurological Cancer	2021	View \| Download
Isatuximab in addition to bortezomib, lenalidomide and dexamethasone for newly diagnosed transplant-ineligible multiple myeloma – first line	Bortezomib (Velcade; bortezomib mannitol boronic ester) , Dexamethasone (dexamethasone sodium metasulfobenzoate) , Isatuximab (SAR650984; Sarclisa) , Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2021	View \| Download
Inolimomab for acute Graft versus Host Disease	Inolimomab (Leukotac; B-B10; BT563)	Graft versus host disease (GvHD)	Immunology	2021	View \| Download
Infigratinib for unresectable locally advanced or metastatic cholangiocarinoma with FGFR2 rearrangements – second line	Infigratinib (BGJ398; BGJ-398; Truseltiq)	Cholangiocarcinoma	Gastrointestinal Cancer	2021	View \| Download
Glofitamab for relapsed or refractory diffuse large B-cell lymphoma	Glofitamab (RG-6026)	Diffuse large B-cell lymphoma (DLBCL) , High grade B cell lymphoma (HGBCL) , Primary mediastinal large B-cell lymphoma (PMBCL)	Haematological Cancer and Lymphomas	2021	View \| Download