Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 12 Results

Title
Intervention Indication Therapeutic Area Year Actions
131I-omburtamab for neuroblastoma with central nervous system or leptomeningeal metastasis in paediatric patients Omburtamab I-131 (131I-mu8H9) Neuroblastoma Neurological Cancer 2019 View  |  Download
Asinercept (Apocept) for glioblastoma multiforme for first or second line Asunercept (Apocept; APG101) Glioma Neurological Cancer 2017 View  |  Download
Dabrafenib with trametinib for treating paediatric BRAF V600 mutated high-grade or low-grade glioma Dabrafenib (Tafinlar; GSK2118436; dabrafenib mesilate) , Trametinib (Mekinist; TMT212; GSK-1120212B; GSK1120212; JTP-74057; trametinib dimethyl sulfoxide) Glioma Neurological Cancer 2022 View  |  Download
Depatuxizumab mafodotin for newly diagnosed EGFR‐amplified glioblastoma – first line Depatuxizumab mafodotin (ABT-414) , Temozolomide (Temodar; Temodal; SCH 52365) Glioma Neurological Cancer 2018 View  |  Download
ERC1671 (Gliovac) for recurrent grade IV glioma Bevacizumab (Avastin; R 435; RG 405; RG 435) , ERC1671 (Gliovac) Glioma Neurological Cancer 2019 View  |  Download
LAM-561 in addition to radiation therapy and temozolomide for glioblastoma –adjuvant 2-hydroxyoleic acid (2-OHOA; LP561A1; LAM561) , Radiotherapy , Temozolomide (Temodar; Temodal; SCH 52365) Glioma Neurological Cancer 2021 View  |  Download
MTX-110 for newly-diagnosed diffuse intrinsic pontine glioma Panobinostat (MTX-110; Farydak; LBH589; LBH-589; panobinostat lactate anhydrous) Glioma Neurological Cancer 2019 View  |  Download
Naxitamab in combination with granulocyte-macrophage colony stimulation factor for relapsed/refractory high-risk neuroblastoma Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF; GM-CSF vaccine) , Naxitamab (Hu3F8; Danyelza) Neuroblastoma Neurological Cancer 2020 View  |  Download
Nivolumab in addition to radiation therapy for glioblastoma – first line Nivolumab (Opdivo; BMS-936558; ONO-4538) , Radiation Glioma Neurological Cancer 2018 View  |  Download
Nivolumab in addition to temozolomide and radiotherapy for MGMT-methylated glioblastoma in newly diagnosed adults - first line Nivolumab (Opdivo; BMS-936558; ONO-4538) , Radiation , Temozolomide (Temodar; Temodal; SCH 52365) Glioma Neurological Cancer 2019 View  |  Download
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