Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
JNJ-68284528 for relapsed or refractory multiple myeloma	Ciltacabtagene Autoleucel (JNJ-68284528; LCAR-B38M CAR-T cell therapy; LCAR-B38M; JNJ 4528)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
JZP-458 for acute lymphoblastic leukaemia and lymphoblastic lymphoma	JZP-458 (RC-P; Recombinant Erwinia asparaginase)	Acute lymphoblastic leukaemia (ALL) , Lymphoblastic lymphoma (LBL)	Haematological Cancer and Lymphomas	2020	View \| Download
KTE-C19 for relapsed or refractory mantle cell lymphoma	Axicabtagene Ciloleucel (Yescarta; KTE-C19)	Mantle cell lymphoma	Haematological Cancer and Lymphomas	2017	View \| Download
KTE-C19 for Relapsed/Refractory B-precursor Acute Lymphocytic Leukaemia in Adults	Brexucabtagene autoleucel (Tecartus; KTE-X19)	Acute lymphoblastic leukaemia (ALL)	Haematological Cancer and Lymphomas	2018	View \| Download
Larotrectinib (LOXO-101) for advanced solid cancers [with an NTRK1, NTRK2, or NTRK3 gene fusion]	Larotrectinib (LOXO-101; Viktravi; larotrectinib sulfate)	Solid tumours	Haematological Cancer and Lymphomas , Oncology	2017	View \| Download
Lenalidomide (Revlimid) + rituximab for relapsed/refractory follicular lymphoma and marginal zone lymphoma	Lenalidomide (Revlimid) , Rituximab (MabThera; Rituxan; RG 105)	Follicular lymphoma , Marginal zone lymphoma (MZL)	Haematological Cancer and Lymphomas	2017	View \| Download
Lenalidomide (Revlimid) for Newly Diagnosed Multiple Myeloma – First Line	Lenalidomide (Revlimid)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2017	View \| Download
Lenalidomide (Revlimid) in combination with rituximab for untreated follicular lymphoma	Lenalidomide (Revlimid) , Rituximab (MabThera; Rituxan; RG 105)	Follicular lymphoma	Haematological Cancer and Lymphomas	2017	View \| Download
Lenalidomide in addition to R-CHOP chemotherapy for diffuse large B-cell lymphoma	Lenalidomide (Revlimid) , R-CHOP	Diffuse large B-cell lymphoma (DLBCL)	Haematological Cancer and Lymphomas	2019	View \| Download
Liposomal cytarabine-daunorubicin for treating relapsed or refractory acute myeloid leukaemia in paediatric patients.	CPX-351 (Vyxeos Liposomal) (fixed dose combination: Cytarabine; daunorubicin)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2020	View \| Download