Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Histamine dihydrochloride (Ceplene) in combination with low dose interleukin-2 as maintenance treatment for acute myeloid leukaemia	Histamine dihydrochloride (Ceplene) , Low-dose aldesluekin	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2019	View \| Download
Guselkumab for active psoriatic arthritis	Guselkumab (Tremfya; CNTO-1959)	Psoriatic arthritis	Dermatology , Rheumatology	2019	View \| Download
Fostemsavir for HIV-1 infection for heavily treatment-experienced adults	Fostemsavir (GSK3684934; BMS-663068)	HIV-1 infection	Infectious Disease	2019	View \| Download
Filgotinib for moderately to severely active ulcerative colitis	Filgotinib (GLPG-0634; filgotinib maleate)	Ulcerative colitis	Gastroenterology	2019	View \| Download
Filgotinib for moderate to severe active rheumatoid arthritis	Filgotinib (GLPG-0634; filgotinib maleate) , Methotrexate (MTX; Otrexup; Vibex MTX; MQX-5902; methotrexate disodium; methotrexate sodium) , other nonbiologic DMARDs	Rheumatoid arthritis	Rheumatology	2019	View \| Download
Fevipiprant maintenance therapy for uncontrolled asthma – add on therapy	Fevipiprant (QAW-039)	Asthma	Respiratory System	2019	View \| Download
Fenfluramine hydrochloride for treatment of seizures associated with Lennox-Gastaut syndrome	Fenfluramine (Brabafen; ZX008; fenfluramine hydrochloride)	Lennox-Gastaut syndrome	Neurology	2019	View \| Download
Evinacumab for homozygous familial hypercholesterolemia	Evinacumab (REGN1500)	Hyperlipidaemia	Endocrine Nutritional and Metabolic Disorders	2019	View \| Download
Esketamine (nasal spray) for major depressive disorder with imminent risk of suicide	Esketamine (JNJ-54135419; Keyzilen; AM-101; esketamine hydrochloride)	Major depressive disorder (MDD)	Mental and Behavioural Health	2019	View \| Download
ERC1671 (Gliovac) for recurrent grade IV glioma	Bevacizumab (Avastin; R 435; RG 405; RG 435) , ERC1671 (Gliovac)	Glioma	Neurological Cancer	2019	View \| Download