Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Diroximel fumarate for relapsing-remitting multiple sclerosis	Diroximel fumarate (BIIB098; ALKS-8700)	Multiple sclerosis (MS)	Neurology	2019	View
Daratumumab (subcutaneous injection) for multiple myeloma	Daratumumab (Darzalex; JNJ-54767414)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2019	View \| Download
Dapagliflozin for heart failure with preserved ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download
Dapagliflozin for chronic heart failure with reduced ejection fraction	Dapagliflozin (Forxiga; BMS512148; Farxiga; dapagliflozin propanediol monohydrate)	Heart failure (HF)	Cardiovascular System	2019	View \| Download
Cediranib in combination with olaparib for recurrent platinum-resistant ovarian cancer – fourth line or greater	Cediranib (Recentin; AZD2171) , Olaparib (Lynparza; MK-7339; AZD2281; AZD-2281)	Epithelial ovarian cancer , Fallopian tube cancer , primary peritoneal cancer	Female Reproductive Cancer	2019	View \| Download
Carfilzomib in addition to daratumumab and dexamethasone for relapsed and/or refractory multiple myeloma	Carfilzomib (Kyprolis; ONO-7057) , Daratumumab (Darzalex; JNJ-54767414) , Dexamethasone (dexamethasone sodium metasulfobenzoate)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2019	View \| Download
Canagliflozin for chronic kidney disease in adult patients with type 2 diabetes mellitus	Canagliflozin (Invokana; canagliflozin hemihydrate)	Diabetic nephropathy	Endocrine Nutritional and Metabolic Disorders , Nephrology	2019	View \| Download
Cabotegravir in combination with rilpivirine long acting injection for the treatment of HIV-1 infection	Cabotegravir (GSK1265744) , Rilpivirine hydrochloride (Edurant)	HIV-1 infection	Infectious Disease	2019	View \| Download
Cabotegravir (oral tablet) in combination with rilpivirine (oral tablet) for the short-term treatment of HIV-1 infection	Cabotegravir (GSK1265744) , Rilpivirine hydrochloride (Edurant)	HIV-1 infection	Infectious Disease	2019	View \| Download
Bupivacaine and meloxicam (HTX-011) for post-operative pain	HTX-011 (Zynrelef) (fixed dose combination: Bupivacaine; Meloxicam)	Post-operative pain	Pain Relief	2019	View \| Download