Search All Tech Briefings


Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available.  Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 20 Results

Title
Intervention Indication Therapeutic Area Year Actions
Iomab-B for active, relapsed or refractory acute myeloid leukaemia in older patients (aged 55 years and older) I-131-Apamistamab (Iomab-B) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2017 View  |  Download
Ivosidenib for acute myeloid leukaemia with IDH1 mutation Ivosidenib (Tibsovo; AG-120) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2018 View  |  Download
Ivosidenib with azacitidine for previously untreated acute myeloid leukaemia with an IDH1 mutation Azacitidine (Vidaza; CC-486) , Ivosidenib (Tibsovo; AG-120) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2022 View  |  Download
Liposomal cytarabine-daunorubicin for treating relapsed or refractory acute myeloid leukaemia in paediatric patients. CPX-351 (Vyxeos Liposomal) (fixed dose combination: Cytarabine; daunorubicin) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2020 View  |  Download
Pevonedistat in addition to azacitidine for Higher-Risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia and Low Blast Acute Myeloid Leukemia – first-line Azacitidine (Vidaza; CC-486) , Pevonedistat (MLN-4924; TAK-924) Acute myeloid leukaemia (AML) , Chronic myelomonocytic leukaemia (CMML) , Myelodysplastic syndrome (MDS) Haematological Cancer and Lymphomas 2020 View  |  Download
Phelinun for reduced intensity conditioning treatment prior to allogeneic haematopoietic stem cell transplantation Melphalan hydrochloride (Cydex; CDX-353; Phelinun) Acute myeloid leukaemia (AML) , Hodgkin lymphoma , Multiple myeloma (MM) , Neuroblastoma , Non-Hodgkin lymphoma (NHL) , Ovarian cancer Female Reproductive Cancer , Haematological Cancer and Lymphomas , Neurological Cancer 2021 View  |  Download
Quizartinib with chemotherapy for FLT3-ITD positive acute myeloid leukaemia Quizartinib (AC220) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2021 View  |  Download
Treosulfan in combination with Fludarabine for Malignant and Non-Malignant diseases - prior to stem cell transplantation Fludarabine (fludarabine phosphate) , Treosulfan (Ovastat) Acute myeloid leukaemia (AML) , Myelodysplastic syndrome (MDS) Haematological Cancer and Lymphomas 2018 View  |  Download
Venetoclax in combination with a hypomethylating agent or low dose cytarabine for newly diagnosed acute myeloid leukaemia hypomethylating agent , Low-dose cytarabine , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2018 View  |  Download
Venetoclax with azacitidine for treating acute myeloid leukaemia following allogeneic stem cell transplantation Azacitidine (Vidaza; CC-486) , Venetoclax (Venclyxto; ABT-199; Venclexta; GDC-0199) Acute myeloid leukaemia (AML) Haematological Cancer and Lymphomas 2024 View  |  Download
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