Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Lasmiditan for acute treatment of migraine	Lasmiditan (COL-144; LY573144)	Migraine	Neurology	2020	View \| Download
Lecanemab for treating early Alzheimer's disease	Lecanemab (BAN2401)	Alzheimer's disease	Neurology	2021	View \| Download
Lenti‐D for adrenoleukodystrophy in boys	Elivaldogene tavalentivec (Lenti-D)	Adrenoleukodystrophy (ALD)	Genetic Disorders , Neurology	2017	View \| Download
Leriglitazone for X-linked andrenoleukodystrophy	Leriglitazone (MIN-102)	X-linked adrenoleukodystrophy (X-ALD)	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders , Neurology	2023	View \| Download
Levodopa, carbidopa monohydrate and entacapone intestinal gel for severe motor fluctuations in advanced Parkinson’s Disease	Carbidopa (carbidopa monohydrate) , Entacapone (Comtess; OR-611) , Levodopa (ND0612; Inbrija; CVT-30)	Parkinson's disease	Neurology	2021	View \| Download
Levosimendan for respiratory function in amyotrophic lateral sclerosis	Levosimendan (OR1259; Simdax; Leximda)	Respiratory dysfunction	Neurology , Respiratory System	2020	View \| Download
Masitinib with Riluzole for amyotrophic lateral sclerosis	Masitinib , Riluzole	Amyotrophic lateral sclerosis	Neurology	2022	View \| Download
Mexiletine for the Symptomatic Treatment of Myotonic Disorders – First Line	Mexiletine hydrochloride (Namuscla)	Myotonia	Musculoskeletal System , Neurology	2018	View \| Download
Mirabegron for neurogenic detrusor overactivity in people aged 3 to 17 years	Mirabegron	Neurogenic detrusor overactivity	Neurology , Urology	2022	View \| Download
Natalizumab (subcutaneous injection) for highly active relapsing remitting multiple sclerosis	Natalizumab (BG00002; Tysabri; Antegren; AN-100226; ELND-002)	Multiple sclerosis (MS)	Neurology	2021	View \| Download