Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Clostridium botulinum neurotoxin A (Xeomin) for lower limb spasticity due to cerebral palsy – first line	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Lower limb spasticity	Musculoskeletal System , Neurology	2017	View \| Download
Cladribine for treating relapsing-remitting multiple sclerosis	Cladribine	Multiple sclerosis (MS)	Neurology	2023	View \| Download
Cenobamate for Partial Focal Epilepsy – Adjunctive Therapy	Cenobamate (YKP3089)	Epilepsy	Neurology	2018	View \| Download
Cenobamate as an adjunctive therapy for primary generalised tonic-clonic seizures	Cenobamate (YKP3089)	Primary generalised tonic-clonic seizures	Neurology	2022	View \| Download
Cannabidiol in a pharmaceutical formulation (Epidiolex; GWP42003-P) for Lennox-Gastaut syndrome in children and adults	Cannabidiol (BRCX-014; Epidiolex; GW42003; GWP42003; GWP-42003; PG-DN-20WS)	Lennox-Gastaut syndrome	Neurology	2017	View \| Download
Botulinum toxin type A for preventing episodic migraine	Botulinum toxin A (Dysport; AbobotulinumtoxinA; Xeomin; Incobotulinumtoxin A; ANT-1207; Botox; OnabotulinumtoxinA; RT002; Daxibotulinumtoxin A; Azzalure; RT-001; NT 201; AGN-151607)	Migraine	Neurology	2023	View \| Download
Biotin for Adrenomyeloneuropathy without cerebral involvement	Biotin (MD1003; Qizenday; Vitamin B7)	Adrenomyeloneuropathy (AMN)	Genetic Disorders , Neurology	2017	View \| Download
BIIB092 for progressive supranuclear palsy	Gosuranemab (BIIB092; BMS-986168; IPN007)	Progressive supranuclear palsy (PSP)	Neurology	2019	View \| Download
Atogepant for prevention of migraine	Atogepant (AGN-241689; MK-8031)	Migraine	Neurology	2022	View \| Download
Arimoclomol for Niemann-Pick Disease type C - add-on therapy	Arimoclomol (BRX-345)	Niemann-Pick Disease	Endocrine Nutritional and Metabolic Disorders , Genetic Disorders , Neurology	2017	View \| Download