Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

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Title	Intervention	Indication	Therapeutic Area	Year	Actions
Filgotinib for moderate to severe active rheumatoid arthritis	Filgotinib (GLPG-0634; filgotinib maleate) , Methotrexate (MTX; Otrexup; Vibex MTX; MQX-5902; methotrexate disodium; methotrexate sodium) , other nonbiologic DMARDs	Rheumatoid arthritis	Rheumatology	2019	View \| Download
Filgotinib for moderately to severely active ulcerative colitis	Filgotinib (GLPG-0634; filgotinib maleate)	Ulcerative colitis	Gastroenterology	2019	View \| Download
Fostemsavir for HIV-1 infection for heavily treatment-experienced adults	Fostemsavir (GSK3684934; BMS-663068)	HIV-1 infection	Infectious Disease	2019	View \| Download
Guselkumab for active psoriatic arthritis	Guselkumab (Tremfya; CNTO-1959)	Psoriatic arthritis	Dermatology , Rheumatology	2019	View \| Download
Histamine dihydrochloride (Ceplene) in combination with low dose interleukin-2 as maintenance treatment for acute myeloid leukaemia	Histamine dihydrochloride (Ceplene) , Low-dose aldesluekin	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2019	View \| Download
Human acellular vessel for vascular access for haemodialysis in end-stage renal disease	Human Acellular Vessel (HumaGraft; Humacyl)	Arterial venous access	Cardiovascular System	2019	View \| Download
Ibalizumab in combination with other antiretroviral(s) for multidrug-resistant HIV-1 infection	Ibalizumab (Trogarzo; TNX-355)	HIV infection	Infectious Disease	2019	View \| Download
Ibrutinib in addition to rituximab for chronic lymphocytic leukaemia – first-line	Ibrutinib (Imbruvica)	Chronic lymphocytic leukaemia (CLL)	Haematological Cancer and Lymphomas	2019	View \| Download
Idasanutlin in addition to cytarabine for relapsed or refractory acute myeloid leukaemia	Cytarabine , Idasanutlin (RG7388; RO5503781)	Acute myeloid leukaemia (AML)	Haematological Cancer and Lymphomas	2019	View \| Download
Imlifidase for kidney transplantation in highly sensitised patients with chronic kidney disease	Imlifidase (IdeS)	Chronic kidney disease (CKD)	Cardiovascular System , Nephrology	2019	View \| Download