Search All Tech Briefings

Search technology briefings produced by NIHR Innovation Observatory. These are short reports on new or repurposed medicines that we have already sent to our stakeholders. Only those technologies (medicines) that are within the scope of our stakeholders will have a technology briefing available. Search our technology briefings by intervention (drug or device), specific indication (disease or condition), or general therapeutic area.

| 150 Results

Clear All Filters

Title	Intervention	Indication	Therapeutic Area	Year	Actions
Ipatasertib in combination with abiraterone and prednisone for metastatic castrate resistant prostate cancer – first line	Abiraterone acetate (Zytiga; Yonsa) , Ipatasertib (GDC-0068; RG7440) , Prednisone (Decadron; Lodotra)	Prostate cancer	Male Reproductive Cancer	2020	View \| Download
Istradefylline for patients with Parkinson’s disease experiencing end of dose fluctuations	Istradefylline (Nouriast; KW-6002)	Parkinson's disease	Neurology	2020	View \| Download
JNJ-68284528 for relapsed or refractory multiple myeloma	Ciltacabtagene Autoleucel (JNJ-68284528; LCAR-B38M CAR-T cell therapy; LCAR-B38M; JNJ 4528)	Multiple myeloma (MM)	Haematological Cancer and Lymphomas	2020	View \| Download
JZP-458 for acute lymphoblastic leukaemia and lymphoblastic lymphoma	JZP-458 (RC-P; Recombinant Erwinia asparaginase)	Acute lymphoblastic leukaemia (ALL) , Lymphoblastic lymphoma (LBL)	Haematological Cancer and Lymphomas	2020	View \| Download
Lasmiditan for acute treatment of migraine	Lasmiditan (COL-144; LY573144)	Migraine	Neurology	2020	View \| Download
Lenvatinib in addition to everolimus or pembrolizumab for advanced renal cell carcinoma – First line	Everolimus (Zortress; RAD001; Afinitor; Certican; RAD-001) , Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Renal cell carcinoma (RCC)	Renal Cancer	2020	View \| Download
Lenvatinib in combination with pembrolizumab for advanced endometrial cancer – second line	Lenvatinib (Kisplyx; E7080; lenvatinib mesilate) , Pembrolizumab (Keytruda; MK-3475)	Endometrial cancer	Female Reproductive Cancer	2020	View \| Download
Levosimendan for respiratory function in amyotrophic lateral sclerosis	Levosimendan (OR1259; Simdax; Leximda)	Respiratory dysfunction	Neurology , Respiratory System	2020	View \| Download
Lifileucel for unresectable or metastatic melanoma – second-line or greater	Lifileucel (Contego; LN-144) IB	Melanoma	Skin Cancer	2020	View \| Download
Liposomal bupivacaine for post-operative pain	Liposomal bupivacaine (Exparel)	Post-operative pain	Pain Relief	2020	View \| Download